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Avidity Partners: 13F holdings, Q2 2026

Emerging, concentrated · SEC EDGAR filings (CIK 0001791827) · Explore on the interactive board

Avidity Partners disclosed 45 US equity positions worth $624.4m in its Q2 2026 13F filing (holdings as of June 30, 2026, filed August 14, 2026). Its largest position is DNTH at 32.8% of the reported book, followed by CGON, ORKA. The top ten holdings are 81.9% of the book, and the portfolio behaves like about 6 equal-weight positions. Versus the prior filing it opened 15 new positions, added to 11, reduced 6 and exited 15.

$624.4mreported US equity book
45positions
32.8%largest position
81.9%top 10 weight
6.39effective positions (1/HHI)
27quarters on file since Q4 2019

What does Avidity Partners own? Top holdings as of June 30, 2026

Change is measured in shares against the previous filing (Q1 2026), so price moves do not read as decisions. This quarter: 15 new, 11 added, 6 reduced, 15 exited.

#StockSectorWeightValueSharesΔ sharesAction
1 DNTH DIANTHUS THERAPEUTICS INC Healthcare 32.8%$205.1m2,104,184 0% held
2 CGON CG ONCOLOGY INC Healthcare 15.9%$99.4m1,398,948 9% added
3 ORKA ORUKA THERAPEUTICS INC Healthcare 11.6%$72.4m760,424 0% held
4 JBIO JADE BIOSCIENCES INC 6.1%$37.8m1,700,708 21% added
5 ELVN ENLIVEN THERAPEUTICS INC Healthcare 4.5%$27.9m550,000 38% added
6 CATX PERSPECTIVE THERAPEUTICS INC 3.4%$21.5m6,299,999 4% added
7 AKTS AKTIS ONCOLOGY INC 2.5%$15.6m484,200 3% added
8 PALVELLA THERAPEUTICS INC NE 1.7%$10.7m70,000 0% held
9 MOBIA MED INC 1.7%$10.7m798,282 new
10 RGEN REPLIGEN CORP Healthcare 1.7%$10.6m77,800 0% held
11 IMUX IMMUNIC INC 1.6%$10.3m669,941 new
12 SENS SENSEONICS HLDGS INC 1.5%$9.1m1,600,000 new
13 KPTI KARYOPHARM THERAPEUTICS INC 1.4%$9.0m924,487 99% added
14 TEVA TEVA PHARMACEUTICAL INDS LTD Healthcare 1.1%$6.8m200,000 -56% reduced
15 DXCM DEXCOM INC Healthcare 1.1%$6.7m100,000 11% added
16 TEM TEMPUS AI INC Healthcare 1.0%$6.1m105,000 320% added
17 MDT MEDTRONIC PLC Healthcare 0.9%$5.5m70,000 -30% reduced
18 VIR VIR BIOTECHNOLOGY INC Healthcare 0.8%$5.3m519,300 -45% reduced
19 GPCR STRUCTURE THERAPEUTICS INC Healthcare 0.8%$5.3m98,000 227% added
20 EHC ENCOMPASS HEALTH CORP Healthcare 0.7%$4.2m42,000 0% held
21 TENX TENAX THERAPEUTICS INC 0.6%$3.9m265,934 23% added
22 NVCT NUVECTIS PHARMA INC 0.6%$3.7m200,000 new
23 PODD INSULET CORP Healthcare 0.6%$3.7m24,000 new
24 BSX BOSTON SCIENTIFIC CORP Healthcare 0.5%$3.4m80,000 33% added
25 MSLE SATELLOS BIOSCIENCE INC 0.5%$3.0m387,769 0% held
26 ALMR ALAMAR BIOSCIENCES INC 0.5%$3.0m110,000 new
27 CNTX CONTEXT THERAPEUTICS INC 0.4%$2.8m4,998,267 0% held
28 GILD GILEAD SCIENCES INC Healthcare 0.4%$2.5m20,000 0% held
29 CRL CHARLES RIV LABS INTL INC Healthcare 0.4%$2.3m10,000 new
30 PHAT PHATHOM PHARMACEUTICALS INC 0.3%$2.2m200,000 -20% reduced
31 AVALYN PHARMACEUTICALS INC 0.3%$2.0m60,000 new
32 KAILERA THERAPEUTICS INC 0.3%$1.8m80,000 new
33 GMAB GENMAB A/S Healthcare 0.2%$1.4m50,000 0% held
34 NTLA INTELLIA THERAPEUTICS INC Healthcare 0.2%$1.3m75,000 0% held
35 CRVS CORVUS PHARMACEUTICALS INC Healthcare 0.2%$1.2m80,000 -30% reduced
36 ODD ODDITY TECH LTD Consumer Defensive 0.2%$1.1m70,000 0% held
37 SCYX SCYNEXIS INC 0.2%$1.1m260,206 new
38 EVMN EVOMMUNE INC 0.2%$996.8k75,000 new
39 ABT ABBOTT LABORATORIES Healthcare 0.1%$907.4k10,000 new
40 BBIO BRIDGEBIO PHARMA INC Healthcare 0.1%$744.8k10,000 new
41 PTON PELOTON INTERACTIVE INC Consumer Cyclical 0.1%$591.0k100,000 -50% reduced
42 LEGN LEGEND BIOTECH CORP Healthcare 0.1%$433.2k15,000 new
43 BRIDGEBIO ONCOLOGY THERAPEUT 0.1%$334.2k43,853 0% held
44 SVRA SAVARA INC Healthcare 0.0%$308.0k50,000 new
45 TRVI TREVI THERAPEUTICS INC Healthcare 0.0%$124.2k6,660 0% held

What did Avidity Partners sell? Positions exited since the previous filing

StockPrior weightPrior value
IMUX IMMUNIC INC28.7%$7.4m
CNC CENTENE CORP8.8%$2.3m
SCYX SCYNEXIS INC7.4%$1.9m
NTRA NATERA INC6.9%$1.8m
ICLR ICON PLC6.8%$1.8m
KVUE KENVUE INC ORD6.7%$1.7m
HIMS HIMS & HERS HEALTH INC6.0%$1.6m
RVMD REVOLUTION MEDICINES INC5.6%$1.5m
CORT CORCEPT THERA4.7%$1.2m
ABVX ABIVAX SA-ADR4.3%$1.1m
UNH UNITEDHEALTH GRP4.0%$1.0m
MLTX MOONLAKE IMMUNOTHERAPEUTICS3.6%$932.0k
AVR ANTERIS TECHNOLOGIES GLOBAL3.2%$832.5k
ABUS ARBUTUS BIOPHARMA CORP2.2%$562.5k
ACAD ACADIA PHARM1.1%$288.6k

Sector mix

SectorWeight
Healthcare75.8%
Consumer Defensive0.2%
Consumer Cyclical0.1%

Sectors cover positions whose ticker resolved to a sector; the remainder is unclassified, not cash.

Filing history

QuarterPositionsEquity value
Q2 202645$624.4m
Q1 202645$493.8m
Q4 202539$346.7m
Q3 202543$439.4m
Q2 202555$498.8m
Q1 202563$484.9m
Q4 202461$1.0bn
Q3 202481$2.0bn
Q2 202485$2.4bn
Q1 202487$2.8bn
Q4 202372$2.6bn
Q3 202383$2.5bn
Q2 202393$2.9bn
Q1 202383$3.0bn
Q4 202284$4.3bn
Q3 202296$4.6bn

Earliest filing: Q4 2019 · 27 quarters on file

How concentrated is Avidity Partners's portfolio?

Across every quarter Avidity Partners has filed, its median largest position is 6.2% of the book and its median top-ten weight is 39.7%, which WhaleCreep classifies as concentrated (the gate is a median largest position of 5%). Of 555 completed holding spells, the median lasted 2.0 quarters; 45 positions are still open and their final length is unknown.