| Superstring Capital Management LP Hedge fund | 8.3% | $13.2m | 53,916 | +381% | added |
| Tri Locum Partners LP Hedge fund | 6.6% | $53.7m | 219,308 | +253% | added |
| Ally Bridge Group (NY) LLC Hedge fund | 5.2% | $4.0m | 16,493 | – | new |
| PFM Health Sciences, LP Hedge fund | 4.7% | $53.8m | 219,596 | −17% | reduced |
| Panoramic Capital, LLC Hedge fund | 4.6% | $10.8m | 44,000 | – | new |
| Iridian Asset Management LLC Hedge fund | 4.0% | $11.7m | 47,924 | −29% | reduced |
| Occam Crest Management LP Hedge fund | 3.7% | $6.8m | 29,800 | −14% | reduced |
| Science & Technology Partners, L.P. Hedge fund | 3.0% | $17.9m | 73,040 | – | new |
| Integral Health Asset Management, LLC Hedge fund | 3.0% | $73.4m | 300,000 | +757% | added |
| Ishara Investments LP Hedge fund | 2.9% | $4.0m | 16,400 | −60% | reduced |
| Eagle Health Investments LP Hedge fund | 2.6% | $15.9m | 65,051 | – | new |
| Deep Track Capital, LP Hedge fund | 2.5% | $171m | 700,000 | −36% | reduced |
| KVP Capital Advisors, LP Hedge fund | 2.2% | $2.9m | 12,000 | −67% | reduced |
| Sofinnova Investments, Inc. Hedge fund | 2.1% | $39.3m | 160,429 | −25% | reduced |
| Catalio Capital Management, LP Hedge fund | 2.0% | $10.6m | 43,182 | – | new |
| Atika Capital Management LLC Hedge fund | 1.5% | $15.4m | 63,000 | – | new |
| Seven Fleet Capital Management LP Hedge fund | 1.2% | $7.1m | 28,826 | +105% | added |
| HighVista Strategies LLC Hedge fund | 1.1% | $4.9m | 20,183 | −1.2% | reduced |
| Samlyn Capital, LLC Hedge fund | 1.0% | $60.2m | 246,015 | – | new |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. Hedge fund | 1.0% | $3.4m | 13,831 | −16% | reduced |
| Twinbeech Capital LP Hedge fund | 0.8% | $4.4m | 18,135 | – | new |
| Birchview Capital, LP Hedge fund | 0.7% | $1.5m | 6,000 | 0.0% | held |
| Stempoint Capital LP Hedge fund | 0.7% | $3.8m | 15,375 | – | new |
| Orbimed Advisors LLC Hedge fund | 0.5% | $28.8m | 117,578 | −45% | reduced |
| Perceptive Advisors LLC Hedge fund | 0.5% | $29.0m | 118,450 | −21% | reduced |
| Ground Swell Capital, LLC Hedge fund | 0.4% | $361k | 1,475 | – | new |
| Voleon Capital Management LP Hedge fund | 0.4% | $20.7m | 84,433 | −43% | reduced |
| Catalyst Funds Management Pty Ltd Hedge fund | 0.3% | $6.1m | 24,900 | – | new |
| Readystate Asset Management LP Hedge fund | 0.3% | $8.2m | 33,554 | – | new |
| Atom Investors LP Hedge fund | 0.3% | $3.5m | 14,179 | +73% | added |
| Hillsdale Investment Management Inc. Hedge fund | 0.3% | $13.5m | 55,000 | +3.1% | added |
| Parkman Healthcare Partners LLC Hedge fund | 0.3% | $2.4m | 10,000 | – | new |
| Weiss Asset Management LP Hedge fund | 0.2% | $19.6m | 80,000 | – | new |
| J. Goldman & Co LP Hedge fund | 0.2% | $5.6m | 23,014 | – | new |
| Scientech Research LLC Hedge fund | 0.2% | $201k | 820 | – | new |
| Dymon Asia Capital (Singapore) Pte. Ltd. Hedge fund | 0.2% | $979k | 4,000 | – | new |
| Point72 Asset Management, L.P. Hedge fund | 0.2% | $102m | 416,516 | −1.9% | reduced |
| Gsa Capital Partners LLP Hedge fund | 0.1% | $2.3m | 9,419 | +294% | added |
| Aquatic Capital Management LLC Hedge fund | 0.1% | $4.0m | 16,297 | – | new |
| Occudo Quantitative Strategies LP Hedge fund | 0.1% | $2.6m | 10,490 | −24% | reduced |
| Fox Run Management, L.L.C. Hedge fund | 0.1% | $810k | 3,308 | – | new |
| Trexquant Investment LP Hedge fund | 0.1% | $20.5m | 83,679 | +1310% | added |
| Two Sigma Investments, LP Hedge fund | 0.1% | $164m | 669,478 | +107% | added |
| Woodline Partners LP Hedge fund | 0.1% | $39.7m | 162,221 | 0.0% | held |
| Persistent Asset Partners Ltd Hedge fund | 0.1% | $385k | 1,573 | – | new |
| Qube Research & Technologies Ltd Hedge fund | 0.1% | $104m | 426,336 | +27% | added |
| Y-Intercept (Hong Kong) Ltd Hedge fund | 0.1% | $5.6m | 22,923 | – | new |
| Brevan Howard Capital Management LP Hedge fund | 0.1% | $7.8m | 31,928 | – | new |
| Cinctive Capital Management LP Hedge fund | 0.1% | $2.7m | 11,121 | – | new |
| ABS Investment Management LLC Hedge fund | 0.1% | $171k | 245 | – | |
| FORA Capital, LLC Hedge fund | 0.1% | $1.6m | 6,364 | +339% | added |
| Millennium Management LLC Hedge fund | 0.09% | $136m | 556,088 | +2579% | added |
| D. E. Shaw & Co., Inc. Hedge fund | 0.09% | $148m | 604,753 | +0.2% | held |
| Adage Capital Partners GP, L.L.C. Hedge fund | 0.09% | $63.4m | 259,034 | −65% | reduced |
| Renaissance Technologies LLC Hedge fund | 0.09% | $64.1m | 262,000 | +59% | added |
| EntryPoint Capital, LLC Hedge fund | 0.08% | $340k | 1,391 | – | new |
| Jain Global LLC Hedge fund | 0.08% | $6.7m | 27,569 | +738% | added |
| Lighthouse Investment Partners, LLC Hedge fund | 0.08% | $2.6m | 10,427 | +573% | added |
| 111 Capital Hedge fund | 0.08% | $450k | 1,839 | – | new |
| Quarry LP Hedge fund | 0.08% | $490k | 2,000 | −60% | reduced |
| Squarepoint Ops LLC Hedge fund | 0.07% | $37.8m | 154,605 | +35% | added |
| AlphaGrep UK Ltd Hedge fund | 0.07% | $230k | 940 | −54% | reduced |
| Rock Springs Capital Management LP Hedge fund | 0.07% | $1.3m | 5,500 | – | new |
| Diametric Capital, LP Hedge fund | 0.06% | $599k | 2,448 | – | new |
| Edgestream Partners, L.P. Hedge fund | 0.06% | $2.1m | 8,718 | – | new |
| Bridgewater Associates, LP Hedge fund | 0.06% | $14.2m | 58,217 | +2.2% | added |
| Hudson Bay Capital Management LP Hedge fund | 0.05% | $10.5m | 43,020 | +183% | added |
| Axiom Investors LLC Hedge fund | 0.05% | $5.5m | 22,631 | −60% | reduced |
| Marshall Wace, LLP Hedge fund | 0.05% | $54.7m | 223,386 | +58% | added |
| Schonfeld Strategic Advisors LLC Hedge fund | 0.05% | $8.7m | 35,608 | – | new |
| Entropy Technologies, LP Hedge fund | 0.04% | $1.1m | 4,473 | −56% | reduced |
| Bayforest Capital Ltd Hedge fund | 0.04% | $41.1k | 168 | −83% | reduced |
| Citadel Advisors LLC Hedge fund | 0.04% | $62.6m | 255,878 | −9.1% | reduced |
| Engineers Gate Manager LP Hedge fund | 0.04% | $2.7m | 11,198 | −32% | reduced |
| Balyasny Asset Management L.P. Hedge fund | 0.03% | $18.7m | 76,250 | – | new |
| WCM Investment Management Long-only investor | 0.03% | $18.3m | 75,713 | −30% | reduced |
| Mirabella Financial Services LLP Hedge fund | 0.03% | $335k | 1,367 | – | new |
| Boothbay Fund Management, LLC Hedge fund | 0.03% | $1.6m | 6,436 | – | new |
| Prelude Capital Management, LLC Hedge fund | 0.03% | $372k | 1,520 | – | new |
| PDT Partners, LLC Hedge fund | 0.03% | $514k | 2,100 | 0.0% | held |
| BTG Pactual Asset Management US LLC Hedge fund | 0.02% | $320k | 1,309 | – | new |
| Dark Forest Capital Management LP Hedge fund | 0.02% | $319k | 1,304 | – | new |
| Laurion Capital Management LP Hedge fund | 0.02% | $283k | 1,155 | – | new |
| Caxton Associates LLP Hedge fund | 0.02% | $1.1m | 4,290 | −0.5% | held |
| Tudor Investment Corp ET AL Hedge fund | 0.02% | $4.6m | 18,950 | – | new |
| Arrowstreet Capital, Limited Partnership Hedge fund | 0.01% | $33.1m | 135,195 | – | new |
| Alyeska Investment Group, L.P. Hedge fund | 0.01% | $4.9m | 20,091 | – | new |
| Verition Fund Management LLC Hedge fund | 0.01% | $1.5m | 6,000 | – | new |
| AQR Capital Management LLC Hedge fund | 0.01% | $27.9m | 114,025 | +9.6% | added |
| Polen Capital Long-only investor | 0.01% | $1.1m | 4,468 | +111% | added |
| Walleye Capital LLC Hedge fund | 0.0% | $420k | 1,716 | −95% | reduced |
| Quantbot Technologies LP Hedge fund | 0.0% | $24.2k | 99 | – | new |