Which hedge funds own KPTI? KARYOPHARM THERAPEUTICS INC, Q2 2026 13F holders
24 tracked hedge funds disclosed a position in KPTI (KARYOPHARM THERAPEUTICS INC) in their Q2 2026 13F filings, worth $95.4m in total. The largest holder by portfolio weight is Catalio Capital Management, LP at 1.7% of its book. 7 opened a new position this quarter: Silverarc Capital Management, LLC, Ghisallo Capital Management LLC, J. Goldman & Co LP, ExodusPoint Capital Management, LP. 9 exited: Commodore Capital LP, Ikarian Capital, LLC, DAFNA Capital Management LLC.
- 24
- Holders Tracked managers whose filing for the quarter reports a long equity position in the security.
- 7
- New this quarter Holders whose previous filing (at most two quarters earlier) did not report the security.
- 9
- Exited this quarter Tracked managers whose previous filing reported the security and whose filing for the quarter does not.
- $9.9m
- Inflow, new holders Combined value of the positions the new holders reported for the quarter.
- $18.2m
- Outflow, exits Combined value the exiting managers reported for the security in their previous filing.
- $95.4m
- Combined value Sum of the holders' reported positions in the security.
- 1.9%
- Share of managers holding Holders as a share of tracked managers filing for that quarter. Comparable across the 2024 coverage expansion, where the raw holder count is not.
Holders, Q2 2026
Exited since the previous filing
| Commodore Capital LP | 0.6% | $10.9m |
| Ikarian Capital, LLC | 0.6% | $4.1m |
| DAFNA Capital Management LLC | 0.06% | $255k |
| Tetragon Partners GP Ltd | 0.06% | $295k |
| ADAR1 Capital Management, LLC | 0.05% | $762k |
| Boothbay Fund Management, LLC | 0.03% | $1.2m |
| Centiva Capital, LP | 0.01% | $168k |
| Zimmer Partners, LP | 0.01% | $209k |
| Balyasny Asset Management L.P. | 0.0% | $394k |
Ownership over time
Who discovered KPTI first? Beta
| Avoro Capital Advisors LLC | Q3 2019 | +1.8 pts |
| Sphera Funds Management Ltd. | Q1 2020 | 0.0 pts |
| Opaleye Management Inc. | Q1 2023 | −1.6 pts |
| Rubric Capital Management LP | Q2 2021 | −1.8 pts |
| Ally Bridge Group (NY) LLC high conviction | Q3 2022 | −2.1 pts |
| Commodore Capital LP high conviction | Q1 2022 | −2.5 pts |
| Birchview Capital, LP | Q1 2020 | −2.6 pts |
| Palo Alto Investors LP high conviction | Q4 2019 | −5.2 pts |
Split-adjusted quarter-end prices, excluding dividends. They describe the stock while each manager held it, not the return it earned.