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Vestal Point Capital, LP 13F holdings, Q3 2025

Holdings as of September 30, 2025 · filings on SEC EDGAR · latest filing →

Vestal Point Capital, LP disclosed 80 US equity positions worth $2.2bn in its Q3 2025 13F filing. The largest position was ASND at 5.4% of the reported book, followed by ACLXGBX and Nuvalent Inc. Against the Q2 2025 filing, it opened 10 new positions, added to 21 and reduced 18 among the top 50 holdings.

← Q2 2025 · Q4 2025 →

What did Vestal Point Capital, LP own in Q3 2025? Top 50 positions

#StockSectorWeightValueSharesΔ sharesvs Q2 2025
1 ASND Ascendis Pharma A/S Healthcare 5.4%$119.3m600,000 200% added
2 ACLXGBX Arcellx Inc 4.7%$102.6m1,250,000 -55% reduced
3 Nuvalent Inc 4.3%$95.1m1,100,000 2% added
4 ABVX Abivax SA 3.9%$84.9m1,000,000 – new
5 ALC Alcon AG Healthcare 3.7%$82.0m1,100,000 110% added
6 BCAX Bicara Therapeutics Inc 3.7%$80.5m5,100,000 2% added
7 AM6 Amicus Therapeutics Inc 3.5%$76.8m9,750,000 -18% reduced
8 GMED Globus Medical Inc Healthcare 3.2%$71.6m1,250,000 150% added
9 IONS Ionis Pharmaceuticals Inc Healthcare 3.2%$70.3m1,075,000 115% added
10 JAZZ Jazz Pharmaceuticals PLC Healthcare 3.0%$65.9m500,000 -58% reduced
11 BDX Becton Dickinson & Co Healthcare 2.8%$60.8m325,000 1200% added
12 SRRK Scholar Rock Holding Corp Healthcare 2.5%$55.9m1,500,000 0% held
13 IMTX Immatics NV Healthcare 2.5%$54.1m6,350,000 2% added
14 RGEN Repligen Corp Healthcare 2.4%$53.5m400,000 – new
15 DNTH Dianthus Therapeutics Inc Healthcare 2.1%$46.4m1,180,000 -63% reduced
16 BMRN BioMarin Pharmaceutical Inc Healthcare 2.0%$45.0m830,000 66% added
17 XENE Xenon Pharmaceuticals Inc Healthcare 2.0%$44.2m1,100,000 -45% reduced
18 DXCM Dexcom Inc Healthcare 2.0%$43.7m650,000 – new
19 CYTK Cytokinetics Inc Healthcare 1.8%$39.8m725,000 -76% reduced
20 BIIB Biogen Inc Healthcare 1.7%$38.5m275,000 – new
21 CDTX Cidara Therapeutics Inc 1.7%$38.3m400,000 -20% reduced
22 CATBUSD Astria Therapeutics Inc 1.6%$36.1m4,956,000 10% added
23 DYN Dyne Therapeutics Inc Healthcare 1.6%$35.1m2,775,000 281% added
24 TYRA Tyra Biosciences Inc Healthcare 1.5%$33.9m2,425,000 -9% reduced
25 ABT Abbott Laboratories Healthcare 1.5%$33.5m250,000 43% added
26 IRON Disc Medicine Inc Healthcare 1.5%$33.0m500,000 257% added
27 NRIX Nurix Therapeutics Inc Healthcare 1.5%$32.1m3,475,000 74% added
28 CRNXGBP Crinetics Pharmaceuticals Inc 1.4%$31.2m750,000 -50% reduced
29 CLDX Celldex Therapeutics Inc Healthcare 1.4%$31.2m1,205,000 -31% reduced
30 ZYME Zymeworks Inc Healthcare 1.4%$30.1m1,765,000 53% added
31 DHR Danaher Corp Healthcare 1.3%$29.7m150,000 200% added
32 RVMD Revolution Medicines Inc Healthcare 1.3%$29.4m630,000 -48% reduced
33 RAPP Rapport Therapeutics Inc 1.3%$28.2m950,000 – new
34 ELVN Enliven Therapeutics Inc Healthcare 1.1%$23.7m1,160,000 364% added
35 GERN Geron Corp Healthcare 1.1%$23.6m17,225,000 -28% reduced
36 BLTE Belite Bio Inc Healthcare 1.0%$23.1m312,500 – new
37 RARE Ultragenyx Pharmaceutical Inc Healthcare 1.0%$22.6m750,000 – new
38 VERA Vera Therapeutics Inc Healthcare 1.0%$22.1m760,000 -75% reduced
39 LXEO Lexeo Therapeutics Inc Healthcare 1.0%$21.6m3,250,000 1% added
40 BDTX Black Diamond Therapeutics Inc 1.0%$21.0m5,550,000 -1% reduced
41 DAWNGBX Day One Biopharmaceuticals Inc 0.9%$18.9m2,675,000 -11% reduced
42 SLDB Solid Biosciences Inc Healthcare 0.8%$18.4m2,975,000 98% added
43 AXSM Axsome Therapeutics Inc Healthcare 0.8%$18.2m150,000 – new
44 TSHA Taysha Gene Therapies Inc Healthcare 0.8%$18.0m5,500,000 83% added
45 APGE Apogee Therapeutics Inc Healthcare 0.8%$16.9m425,000 – new
46 SVRA Savara Inc Healthcare 0.7%$14.3m4,015,000 -64% reduced
47 BRKR Bruker Corp Healthcare 0.6%$14.3m440,000 -12% reduced
48 REGN Regeneron Pharmaceuticals Inc Healthcare 0.6%$14.1m25,000 – new
49 QURE uniQure NV 0.6%$13.1m225,000 -94% reduced
50 BBNX Beta Bionics Inc Healthcare 0.5%$11.9m600,000 9% added

Weights are shares of the reported long US equity book (options excluded). Values are as filed, normalised to whole dollars. Share changes compare against the immediately preceding filing only.