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Vestal Point Capital, LP 13F holdings, Q2 2025

Holdings as of June 30, 2025 · filings on SEC EDGAR · latest filing →

Vestal Point Capital, LP disclosed 72 US equity positions worth $1.9bn in its Q2 2025 13F filing. The largest position was ACLXGBX at 9.5% of the reported book, followed by JAZZ and CYTK. Against the Q1 2025 filing, it opened 14 new positions, added to 22 and reduced 10 among the top 50 holdings.

← Q1 2025 · Q3 2025 →

What did Vestal Point Capital, LP own in Q2 2025? Top 50 positions

#StockSectorWeightValueSharesΔ sharesvs Q1 2025
1 ACLXGBX Arcellx Inc 9.5%$181.1m2,750,000 15% added
2 JAZZ Jazz Pharmaceuticals PLC Healthcare 6.7%$127.3m1,200,000 – new
3 CYTK Cytokinetics Inc Healthcare 5.2%$98.3m2,975,000 15% added
4 Nuvalent Inc 4.3%$82.0m1,075,000 0% held
5 VERA Vera Therapeutics Inc Healthcare 3.8%$73.0m3,100,000 24% added
6 AM6 Amicus Therapeutics Inc 3.6%$68.2m11,900,000 178% added
7 XENE Xenon Pharmaceuticals Inc Healthcare 3.3%$62.6m2,000,000 54% added
8 DNTH Dianthus Therapeutics Inc Healthcare 3.1%$59.6m3,200,000 88% added
9 SRRK Scholar Rock Holding Corp Healthcare 2.8%$53.1m1,500,000 15% added
10 4XC1 KalVista Pharmaceuticals Inc 2.8%$52.9m4,675,000 -2% reduced
11 GEHC GE HealthCare Technologies Inc Healthcare 2.7%$51.8m700,000 243% added
12 QURE uniQure NV 2.7%$51.6m3,700,000 -23% reduced
13 BCAX Bicara Therapeutics Inc 2.4%$46.5m5,000,000 81% added
14 ALC Alcon AG Healthcare 2.4%$46.3m525,000 – new
15 RVMD Revolution Medicines Inc Healthcare 2.3%$44.1m1,200,000 – new
16 CRNXGBP Crinetics Pharmaceuticals Inc 2.3%$43.1m1,500,000 0% held
17 EXK Exact Sciences Corp Basic Materials 2.0%$37.2m700,000 – new
18 CLDX Celldex Therapeutics Inc Healthcare 1.9%$35.6m1,750,000 781% added
19 ASND Ascendis Pharma A/S Healthcare 1.8%$34.5m200,000 33% added
20 IMTX Immatics NV Healthcare 1.8%$33.6m6,250,000 -13% reduced
21 GERN Geron Corp Healthcare 1.8%$33.5m23,775,000 8% added
22 GMED Globus Medical Inc Healthcare 1.6%$29.5m500,000 150% added
23 BMRN BioMarin Pharmaceutical Inc Healthcare 1.4%$27.5m500,000 – new
24 MLTX MoonLake Immunotherapeutics Healthcare 1.4%$26.0m550,000 175% added
25 TYRA Tyra Biosciences Inc Healthcare 1.3%$25.4m2,655,000 -8% reduced
26 SVRA Savara Inc Healthcare 1.3%$25.1m11,015,000 0% held
27 COO Cooper Cos Inc/The Healthcare 1.3%$24.9m350,000 – new
28 GPCR Structure Therapeutics Inc Healthcare 1.3%$24.9m1,200,000 -33% reduced
29 CDTX Cidara Therapeutics Inc 1.3%$24.4m500,000 -1% reduced
30 CATBUSD Astria Therapeutics Inc 1.3%$24.2m4,522,000 8% added
31 ABT Abbott Laboratories Healthcare 1.3%$23.8m175,000 – new
32 EW Edwards Lifesciences Corp Healthcare 1.2%$23.5m300,000 – new
33 NRIX Nurix Therapeutics Inc Healthcare 1.2%$22.8m2,000,000 78% added
34 COGT Cogent Biosciences Inc Healthcare 1.2%$22.1m3,080,000 3% added
35 BRKR Bruker Corp Healthcare 1.1%$20.6m500,000 67% added
36 IONS Ionis Pharmaceuticals Inc Healthcare 1.0%$19.8m500,000 – new
37 DAWNGBX Day One Biopharmaceuticals Inc 1.0%$19.5m3,000,000 15% added
38 MDT Medtronic PLC Healthcare 0.9%$17.0m195,000 – new
39 PRGO Perrigo Co PLC Healthcare 0.9%$16.7m625,000 6% added
40 ZYME Zymeworks Inc Healthcare 0.8%$14.4m1,150,000 130% added
41 BDTX Black Diamond Therapeutics Inc 0.7%$13.9m5,600,000 0% held
42 LXEO Lexeo Therapeutics Inc Healthcare 0.7%$13.0m3,228,161 184% added
43 Nyxoah SA 0.6%$10.5m1,402,002 -40% reduced
44 TMO Thermo Fisher Scientific Inc Healthcare 0.5%$10.1m25,000 – new
45 DHR Danaher Corp Healthcare 0.5%$9.9m50,000 -60% reduced
46 BBNX Beta Bionics Inc Healthcare 0.4%$8.0m550,000 – new
47 IRON Disc Medicine Inc Healthcare 0.4%$7.4m140,000 – new
48 SLDB Solid Biosciences Inc Healthcare 0.4%$7.3m1,505,000 -14% reduced
49 TSHA Taysha Gene Therapies Inc Healthcare 0.4%$6.9m3,000,000 – new
50 DYN Dyne Therapeutics Inc Healthcare 0.4%$6.9m727,500 -60% reduced

Weights are shares of the reported long US equity book (options excluded). Values are as filed, normalised to whole dollars. Share changes compare against the immediately preceding filing only.