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MPM Bioimpact LLC 13F holdings, Q4 2024

Holdings as of December 31, 2024 · filings on SEC EDGAR · latest filing →

MPM Bioimpact LLC disclosed 47 US equity positions worth $704.4m in its Q4 2024 13F filing. The largest position was CGEM at 13.2% of the reported book, followed by CRNXGBP and EWTX. Against the Q3 2024 filing, it opened 11 new positions, added to 21 and reduced 11 among the top 47 holdings.

← Q3 2024 · Q1 2025 →

What did MPM Bioimpact LLC own in Q4 2024? Top 47 positions

#StockSectorWeightValueSharesΔ sharesvs Q3 2024
1 CGEM Cullinan Therapeutics, Inc. Healthcare 13.2%$93.2m7,648,268 0% held
2 CRNXGBP Crinetics Pharmaceuticals Inc. 4.5%$31.5m617,035 17% added
3 EWTX Edgewise Therapeutics Inc 4.1%$28.8m1,079,316 18% added
4 INSM Insmed Incorporated Healthcare 3.8%$26.9m389,611 -37% reduced
5 NTRA Natera Inc Healthcare 3.6%$25.4m160,626 -9% reduced
6 MIRM Mirum Pharmaceuticals Inc Healthcare 3.5%$24.4m589,579 20% added
7 IRON Disc Medicine Inc Healthcare 3.1%$22.0m346,401 11% added
8 LNTH Lantheus Holdings Inc Healthcare 3.0%$21.1m236,213 57% added
9 ZLAB Zai Lab Ltd Healthcare 3.0%$21.0m800,000 – new
10 RNAGBP Avidity Biosciences Inc 2.9%$20.4m702,981 2% added
11 IOVA Iovance Biotherapeutics Inc Healthcare 2.8%$19.8m2,673,905 11% added
12 PTCT PTC Therapeutics Inc Healthcare 2.8%$19.6m434,767 385% added
13 WVE Wave Life Sciences PTE LTD Healthcare 2.6%$18.4m1,489,237 138% added
14 SRRK Scholar Rock Holding Corp. Healthcare 2.6%$18.0m416,144 – new
15 MLTX Moonlake Immunotherapeutics Healthcare 2.4%$17.1m315,230 -10% reduced
16 OLMA Olema Pharmaceuticals, Inc. Healthcare 2.4%$17.0m2,912,550 9% added
17 RARE Ultragenyx Pharmaceutical Inc Healthcare 2.3%$16.5m391,018 19% added
18 CNTX Context Therapeutics Inc 2.2%$15.4m14,705,882 – new
19 GH Guardant Health Inc Healthcare 2.0%$13.8m452,739 -9% reduced
20 RVMD Revolution Medicines, Inc. Healthcare 1.9%$13.7m313,817 8% added
21 2662247D iTeos Therapeutics, Inc. 1.9%$13.4m1,745,943 0% held
22 RNAC Cartesian Therapeutics Inc 1.8%$12.9m721,139 15% added
23 RCKT Rocket Pharmaceuticals, Inc. Healthcare 1.8%$12.8m1,020,559 -4% reduced
24 Akero Therapeutics Inc 1.8%$12.8m460,617 17% added
25 TRVI Trevi Therapeutics Inc Healthcare 1.8%$12.8m3,094,896 101% added
26 TWST Twist Bioscience Corp Healthcare 1.8%$12.4m267,497 -9% reduced
27 CMPX Compass Therapeutics, Inc. 1.8%$12.4m8,567,896 52% added
28 JANX Janux Therapeutics Inc Healthcare 1.7%$12.3m230,000 34% added
29 REPL Replimune Group Inc Healthcare 1.6%$11.5m950,000 – new
30 NUVB Nuvation Bio Inc Healthcare 1.6%$11.1m4,164,178 – new
31 VERA Vera Therapeutics Inc. Healthcare 1.5%$10.9m257,788 – new
32 IDYA Ideaya Biosciences, Inc. Healthcare 1.5%$10.6m414,035 – new
33 RLAY Relay Therapeutics Inc. Healthcare 1.3%$9.3m2,268,825 12% added
34 UTHR United Therapeutics Corp. Healthcare 1.2%$8.1m23,000 – new
35 ARCT Arcturus Therapeutics Holdings Healthcare 1.1%$7.8m459,943 110% added
36 XENE Xenon Pharmaceuticals Inc Healthcare 1.1%$7.7m197,212 19% added
37 STOK Stoke Therapeutics Inc Healthcare 1.1%$7.6m685,826 43% added
38 AQST Aquestive Therapeutics Inc 0.8%$5.7m1,611,833 -10% reduced
39 AXSM Axsome Therapeutics Inc Healthcare 0.6%$4.2m50,000 – new
40 STRO Sutro Biopharma, Inc. Healthcare 0.6%$4.0m2,160,062 -24% reduced
41 HOWL Werewolf Therapeutics, Inc. 0.5%$3.5m2,388,011 0% held
42 DSGN Design Therapeutics Inc Healthcare 0.5%$3.5m559,547 – new
43 ZNTL Zentalis Pharmaceuticals, Inc. Healthcare 0.5%$3.4m1,106,851 -24% reduced
44 VERU Veru Inc. Healthcare 0.4%$2.8m4,285,365 – new
45 ADAPY Adaptimmune Therapeutics plc Healthcare 0.4%$2.7m5,095,912 0% held
46 ALXO ALX Oncology Holdings Inc. Healthcare 0.3%$2.3m1,391,434 -42% reduced
47 RPTX Repare Therapeutics, Inc. 0.2%$1.6m1,231,154 -25% reduced

Weights are shares of the reported long US equity book (options excluded). Values are as filed, normalised to whole dollars. Share changes compare against the immediately preceding filing only.