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MPM Bioimpact LLC 13F holdings, Q1 2025

Holdings as of March 31, 2025 · filings on SEC EDGAR · latest filing →

MPM Bioimpact LLC disclosed 43 US equity positions worth $581.7m in its Q1 2025 13F filing. The largest position was CGEM at 10.0% of the reported book, followed by MDGL and ZLAB. Against the Q4 2024 filing, it opened 6 new positions, added to 25 and reduced 8 among the top 43 holdings.

← Q4 2024 · Q2 2025 →

What did MPM Bioimpact LLC own in Q1 2025? Top 43 positions

#StockSectorWeightValueSharesΔ sharesvs Q4 2024
1 CGEM Cullinan Therapeutics, Inc. Healthcare 10.0%$57.9m7,648,268 0% held
2 MDGL Madrigal Pharmaceuticals Inc Healthcare 5.7%$33.3m100,415 – new
3 ZLAB Zai Lab Ltd Healthcare 5.2%$30.1m833,659 4% added
4 EWTX Edgewise Therapeutics Inc 4.2%$24.3m1,105,444 2% added
5 LNTH Lantheus Holdings Inc Healthcare 3.9%$22.7m232,387 -2% reduced
6 PTCT PTC Therapeutics Inc Healthcare 3.9%$22.4m439,977 1% added
7 NTRA Natera Inc Healthcare 3.8%$22.2m157,047 -2% reduced
8 TRVI Trevi Therapeutics Inc Healthcare 3.7%$21.6m3,428,366 11% added
9 CRNXGBP Crinetics Pharmaceuticals Inc. 3.6%$21.2m631,964 2% added
10 RNAGBP Avidity Biosciences Inc 3.6%$21.1m714,224 2% added
11 GH Guardant Health Inc Healthcare 3.2%$18.9m442,656 -2% reduced
12 UTHR United Therapeutics Corp. Healthcare 3.1%$18.2m58,907 156% added
13 SPRY ARS Pharmaceuticals Inc Healthcare 2.8%$16.5m1,313,104 – new
14 CMPX Compass Therapeutics, Inc. 2.8%$16.0m8,442,783 -1% reduced
15 JANX Janux Therapeutics Inc Healthcare 2.6%$15.3m567,193 147% added
16 RARE Ultragenyx Pharmaceutical Inc Healthcare 2.5%$14.4m398,445 2% added
17 MLTX Moonlake Immunotherapeutics Healthcare 2.1%$12.3m316,049 0% held
18 WVE Wave Life Sciences PTE LTD Healthcare 2.1%$12.2m1,509,580 1% added
19 RVMD Revolution Medicines, Inc. Healthcare 1.9%$11.2m317,083 1% added
20 ALKS Alkermes Plc Healthcare 1.9%$11.1m337,603 – new
21 OLMA Olema Pharmaceuticals, Inc. Healthcare 1.9%$11.0m2,930,446 1% added
22 RCKT Rocket Pharmaceuticals, Inc. Healthcare 1.9%$10.8m1,618,265 59% added
23 2662247D iTeos Therapeutics, Inc. 1.8%$10.4m1,745,943 0% held
24 RNAC Cartesian Therapeutics Inc 1.8%$10.4m790,779 10% added
25 TWST Twist Bioscience Corp Healthcare 1.8%$10.3m261,215 -2% reduced
26 XENE Xenon Pharmaceuticals Inc Healthcare 1.7%$10.2m303,398 54% added
27 VERA Vera Therapeutics Inc. Healthcare 1.7%$10.0m415,719 61% added
28 REPL Replimune Group Inc Healthcare 1.7%$9.6m987,036 4% added
29 IOVA Iovance Biotherapeutics Inc Healthcare 1.6%$9.0m2,708,582 1% added
30 CNTX Context Therapeutics Inc 1.5%$9.0m14,705,882 0% held
31 MBX MBX Biosciences Inc Healthcare 1.4%$8.4m1,132,950 – new
32 NUVB Nuvation Bio Inc Healthcare 1.4%$8.2m4,652,243 12% added
33 ORIC Oric Pharmaceuticals Inc Healthcare 1.3%$7.8m1,399,514 – new
34 IDYA Ideaya Biosciences, Inc. Healthcare 1.2%$7.0m430,161 4% added
35 SLDB Solid Biosciences Inc Healthcare 1.0%$6.1m1,642,356 – new
36 RLAY Relay Therapeutics Inc. Healthcare 1.0%$6.0m2,295,924 1% added
37 STOK Stoke Therapeutics Inc Healthcare 0.8%$4.6m693,988 1% added
38 VERU Veru Inc. Healthcare 0.6%$3.2m6,592,727 54% added
39 HOWL Werewolf Therapeutics, Inc. 0.4%$2.3m2,408,810 1% added
40 DSGN Design Therapeutics Inc Healthcare 0.4%$2.2m562,943 1% added
41 ADAPY Adaptimmune Therapeutics plc Healthcare 0.2%$964.2k4,894,344 -4% reduced
42 RPTX Repare Therapeutics, Inc. 0.1%$808.4k819,924 -33% reduced
43 ALXO ALX Oncology Holdings Inc. Healthcare 0.1%$342.6k550,000 -60% reduced

Weights are shares of the reported long US equity book (options excluded). Values are as filed, normalised to whole dollars. Share changes compare against the immediately preceding filing only.