| Paloma Partners Management Co Hedge fund | 20.3% | $85.3m | 33.86m | – | new |
| Blue Water Life Science Advisors, LP Hedge fund | 10.8% | $17.2m | 114,747 | −53% | reduced |
| Cadian Capital Management, LP Hedge fund | 8.6% | $114m | 757,393 | −2.9% | reduced |
| Deep Track Capital, LP Hedge fund | 7.5% | $509m | 3.39m | +1.6% | added |
| Eagle Health Investments LP Hedge fund | 7.5% | $45.1m | 300,685 | −3.1% | reduced |
| Exome Asset Management LLC Hedge fund | 6.2% | $10.1m | 67,500 | −18% | reduced |
| Science & Technology Partners, L.P. Hedge fund | 5.3% | $31.3m | 208,817 | – | new |
| Aristeia Capital, L.L.C. Hedge fund | 4.4% | $278m | 150.61m | +4.4% | added |
| First Light Asset Management, LLC Hedge fund | 4.0% | $66.3m | 441,586 | +58% | added |
| Summit Partners Public Asset Management, LLC Hedge fund | 3.8% | $145m | 967,697 | +12% | added |
| Warberg Asset Management LLC Hedge fund | 3.7% | $12.6m | 5.00m | – | new |
| Linden Advisors LP Hedge fund | 3.3% | $632m | 299.27m | +41% | added |
| Atika Capital Management LLC Hedge fund | 2.7% | $27.2m | 181,000 | +99% | added |
| RTW Investments, LP Hedge fund | 1.9% | $222m | 1.48m | 0.0% | held |
| Ares Systematic Credit Ltd Hedge fund | 1.8% | $3.0m | 2.30m | +188% | added |
| DeepCurrents Investment Group LLC Hedge fund | 1.7% | $50.1m | 40.28m | – | new |
| Silverarc Capital Management, LLC Hedge fund | 1.7% | $15.0m | 99,826 | +1.3% | added |
| Orbimed Advisors LLC Hedge fund | 1.7% | $87.6m | 583,700 | +34% | added |
| Morgens Waterfall Vintiadis & Co Inc Hedge fund | 1.6% | $2.1m | 14,000 | – | new |
| Aequim Alternative Investments LP Hedge fund | 1.5% | $94.4m | 37.50m | −12% | reduced |
| Samlyn Capital, LLC Hedge fund | 1.4% | $84.3m | 561,876 | +126% | added |
| Casdin Capital, LLC Hedge fund | 1.4% | $27.8m | 185,000 | −41% | reduced |
| Semanteon Capital Management, LP Hedge fund | 1.1% | $251k | 1,672 | – | new |
| Artia Global Partners LP Hedge fund | 1.1% | $5.7m | 38,100 | – | new |
| Formula Growth Ltd Hedge fund | 1.0% | $2.9m | 19,300 | – | new |
| Sandler Capital Management Hedge fund | 0.9% | $1.6m | 10,580 | – | new |
| Tremblant Capital Group Hedge fund | 0.9% | $29.7m | 197,795 | – | new |
| Braidwell LP Hedge fund | 0.8% | $22.2m | 147,850 | −100% | reduced |
| Brandywine Managers, LLC Hedge fund | 0.7% | $1.4m | 9,133 | 0.0% | held |
| Meridiem Capital Partners LP Hedge fund | 0.7% | $14.6m | 97,088 | – | new |
| Occudo Quantitative Strategies LP Hedge fund | 0.7% | $12.4m | 82,847 | +307% | added |
| Parallax Volatility Advisers, L.P. Hedge fund | 0.6% | $17.5m | 12.00m | +20% | added |
| Catalyst Funds Management Pty Ltd Hedge fund | 0.6% | $11.0m | 73,300 | – | new |
| HighVista Strategies LLC Hedge fund | 0.5% | $2.3m | 15,419 | −34% | reduced |
| PFM Health Sciences, LP Hedge fund | 0.5% | $5.5m | 36,701 | – | new |
| Kinetic Partners Management, LP Hedge fund | 0.5% | $19.5m | 129,900 | 0.0% | held |
| IQ EQ FUND MANAGEMENT (SINGAPORE) PRIVATE Ltd Hedge fund | 0.4% | $255k | 1,700 | – | new |
| Two Sigma Investments, LP Hedge fund | 0.4% | $558m | 3.72m | −12% | reduced |
| Hillsdale Investment Management Inc. Hedge fund | 0.4% | $17.2m | 114,384 | −8.0% | reduced |
| Capricorn Fund Managers Ltd Hedge fund | 0.4% | $4.8m | 31,775 | – | new |
| Fox Run Management, L.L.C. Hedge fund | 0.4% | $2.1m | 14,194 | – | new |
| D. E. Shaw & Co., Inc. Hedge fund | 0.3% | $539m | 176.27m | −0.9% | reduced |
| Readystate Asset Management LP Hedge fund | 0.3% | $7.8m | 51,852 | +7.1% | added |
| Baillie Gifford Long-only investor | 0.3% | $343m | 2.28m | −41% | reduced |
| Cinctive Capital Management LP Hedge fund | 0.3% | $7.4m | 49,631 | – | new |
| Farallon Capital Management, L.L.C. Hedge fund | 0.3% | $48.3m | 322,200 | +3928% | added |
| Alyeska Investment Group, L.P. Hedge fund | 0.3% | $97.2m | 647,818 | −57% | reduced |
| TENOR CAPITAL MANAGEMENT Co., L.P. Hedge fund | 0.2% | $16.3m | 13.12m | 0.0% | held |
| ExodusPoint Capital Management, LP Hedge fund | 0.2% | $24.7m | 164,518 | +7.7% | added |
| ABS Investment Management LLC Hedge fund | 0.2% | $345k | 150 | – | |
| Point72 Asset Management, L.P. Hedge fund | 0.2% | $138m | 920,807 | −92% | reduced |
| Persistent Asset Partners Ltd Hedge fund | 0.2% | $641k | 4,275 | +4.6% | added |
| Axiom Investors LLC Hedge fund | 0.2% | $22.0m | 146,458 | −4.9% | reduced |
| Numerai GP LLC Hedge fund | 0.2% | $2.3m | 15,450 | −0.3% | held |
| Weiss Asset Management LP Hedge fund | 0.2% | $16.5m | 109,876 | – | new |
| Quantitative Investment Management, LLC Hedge fund | 0.2% | $1.6m | 10,548 | +40% | added |
| Millennium Management LLC Hedge fund | 0.2% | $251m | 7.62m | +10% | added |
| Squarepoint Ops LLC Hedge fund | 0.2% | $87.0m | 580,133 | +203% | added |
| Engineers Gate Manager LP Hedge fund | 0.2% | $12.8m | 85,180 | +20% | added |
| Y-Intercept (Hong Kong) Ltd Hedge fund | 0.2% | $7.9m | 52,547 | – | new |
| Trexquant Investment LP Hedge fund | 0.1% | $24.0m | 159,869 | +86% | added |
| Atom Investors LP Hedge fund | 0.1% | $1.7m | 11,084 | −53% | reduced |
| Jain Global LLC Hedge fund | 0.1% | $12.2m | 81,417 | – | new |
| Schonfeld Strategic Advisors LLC Hedge fund | 0.1% | $26.9m | 179,482 | +150% | added |
| FORA Capital, LLC Hedge fund | 0.1% | $2.0m | 13,332 | −12% | reduced |
| Landscape Capital Management, L.L.C. Hedge fund | 0.1% | $2.0m | 13,135 | −31% | reduced |
| 111 Capital Hedge fund | 0.1% | $738k | 4,916 | – | new |
| Citadel Advisors LLC Hedge fund | 0.1% | $217m | 1.45m | −91% | reduced |
| Capstone Investment Advisors, LLC Hedge fund | 0.1% | $17.4m | 13.75m | +57% | added |
| Gsa Capital Partners LLP Hedge fund | 0.1% | $1.8m | 11,811 | +157% | added |
| Centiva Capital, LP Hedge fund | 0.1% | $3.2m | 21,598 | – | new |
| Oxford Asset Management LLP Hedge fund | 0.1% | $205k | 1,364 | −50% | reduced |
| Quantbot Technologies LP Hedge fund | 0.10% | $2.5m | 16,402 | – | new |
| AlphaGrep UK Ltd Hedge fund | 0.10% | $317k | 2,116 | −24% | reduced |
| Perceptive Advisors LLC Hedge fund | 0.10% | $6.2m | 41,327 | −86% | reduced |
| Adage Capital Partners GP, L.L.C. Hedge fund | 0.08% | $55.8m | 371,763 | −54% | reduced |
| EntryPoint Capital, LLC Hedge fund | 0.08% | $313k | 2,083 | – | new |
| Walleye Capital LLC Hedge fund | 0.07% | $15.7m | 104,527 | −64% | reduced |
| Polar Capital Holdings Plc Hedge fund | 0.07% | $23.8m | 158,843 | −8.4% | reduced |
| Candriam S.C.A. Hedge fund | 0.06% | $13.5m | 90,197 | +1.1% | added |
| Dark Forest Capital Management LP Hedge fund | 0.06% | $888k | 5,920 | – | new |
| Caxton Associates LLP Hedge fund | 0.06% | $3.0m | 20,127 | +124% | added |
| RWC Asset Management LLP Hedge fund | 0.06% | $1.5m | 1.18m | −6.8% | reduced |
| Campbell & CO Investment Adviser LLC Hedge fund | 0.05% | $1.0m | 6,979 | −86% | reduced |
| Alpine Woods Capital Investors, LLC Hedge fund | 0.05% | $237k | 1,580 | – | new |
| Aquatic Capital Management LLC Hedge fund | 0.05% | $1.5m | 10,105 | +41% | added |
| WCM Investment Management Long-only investor | 0.05% | $25.7m | 167,010 | −1.6% | reduced |
| Polen Capital Long-only investor | 0.04% | $5.2m | 34,372 | −1.0% | reduced |
| Brevan Howard Capital Management LP Hedge fund | 0.04% | $3.0m | 19,677 | – | new |
| Diametric Capital, LP Hedge fund | 0.04% | $359k | 2,392 | – | new |
| Laurion Capital Management LP Hedge fund | 0.04% | $510k | 3,402 | – | new |
| Balyasny Asset Management L.P. Hedge fund | 0.03% | $18.7m | 124,368 | – | new |
| Entropy Technologies, LP Hedge fund | 0.03% | $819k | 5,461 | −11% | reduced |
| Qsemble Capital Management, LP Hedge fund | 0.03% | $249k | 1,659 | – | new |
| Wolverine Asset Management LLC Hedge fund | 0.03% | $2.2m | 14,897 | −100% | reduced |
| Jupiter Asset Management Ltd Hedge fund | 0.03% | $5.6m | 37,453 | −53% | reduced |
| Qube Research & Technologies Ltd Hedge fund | 0.03% | $23.4m | 156,236 | – | new |
| Verition Fund Management LLC Hedge fund | 0.03% | $3.6m | 24,049 | +13% | added |
| Voleon Capital Management LP Hedge fund | 0.03% | $1.4m | 9,266 | −83% | reduced |
| Marshall Wace, LLP Hedge fund | 0.02% | $27.8m | 185,150 | – | new |
| Arrowstreet Capital, Limited Partnership Hedge fund | 0.02% | $51.2m | 341,574 | – | new |
| Prelude Capital Management, LLC Hedge fund | 0.02% | $213k | 1,421 | −91% | reduced |
| Hudson Bay Capital Management LP Hedge fund | 0.01% | $2.9m | 19,360 | – | new |
| SummitTX Capital, L.P. Hedge fund | 0.01% | $328k | 2,186 | – | new |
| AQR Capital Management LLC Hedge fund | 0.01% | $18.3m | 121,668 | −7.3% | reduced |
| Bridgewater Associates, LP Hedge fund | 0.0% | $637k | 4,244 | −68% | reduced |
| Bayforest Capital Ltd Hedge fund | 0.0% | $1.5k | 10 | −96% | reduced |
| CVA Family Office, LLC Family office | 0.0% | $12.6k | 84 | −2.3% | reduced |
| Quarry LP Hedge fund | 0.0% | $6.5k | 43 | – | new |
| Twin Tree Management, LP Hedge fund | 0.0% | $300 | 2 | – | new |