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Avoro Capital Advisors LLC: 13F holdings, Q2 2026

Hedge fund · SEC EDGAR filings (CIK 1633313) · Explore on the interactive board

Avoro Capital Advisors LLC disclosed 26 US equity positions worth $11.1bn in its Q2 2026 13F filing (holdings as of June 30, 2026, filed August 14, 2026). Its largest position is UTHR at 13.5% of the reported book, followed by ASND, KRYS. The top ten holdings are 79.5% of the book, and the portfolio behaves like about 13 equal-weight positions. Versus the prior filing it opened 3 new positions, added to 11, reduced 3 and exited 7. Note: this manager's most recent filing is 3934 quarters behind the newest quarter on file, so these figures are history rather than current positioning.

This manager's most recent filing is 3934 quarter(s) behind the newest quarter on file. Treat these figures as history, not current positioning.
$11.1bnreported US equity book
26positions
13.5%largest position
79.5%top 10 weight
12.69effective positions (1/HHI)
2quarters on file since Q1 2026

What does Avoro Capital Advisors LLC own? Top holdings as of June 30, 2026

Change is measured in shares against the previous filing (Q1 2026), so price moves do not read as decisions. This quarter: 3 new, 11 added, 3 reduced, 7 exited.

#StockSectorWeightValueSharesΔ sharesAction
1 UTHR UNITED THERAPEUTICS CORP Healthcare 13.5%$1.5bn2,777,777 6% added
2 ASND ASCENDIS PHARMA Healthcare 12.2%$1.4bn5,111,111 new
3 KRYS KRYSTAL BIOTECH INC Healthcare 9.6%$1.1bn2,888,888 0% held
4 MDGL MADRIGAL PHARMACEUTICALS INC Healthcare 8.8%$984.4m1,833,333 1% added
5 ARGX ARGENX SE Healthcare 8.3%$927.8m1,000,000 0% held
6 ARWR ARROWHEAD PHARMACEUTICALS INC Healthcare 8.3%$925.6m11,355,555 6% added
7 KYMR KYMERA THERAPEUTICS INC Healthcare 7.7%$857.1m7,474,747 0% held
8 RVMD REVOLUTION MEDICINES INC Healthcare 3.9%$430.2m2,297,000 -2% reduced
9 CYTK CYTOKINETICS INC Healthcare 3.8%$425.9m4,999,999 50% added
10 CELC CELCUITY INC Healthcare 3.2%$355.7m3,400,000 1% added
11 GPCR STRUCTURE THERAPEUTICS INC Healthcare 3.2%$351.8m6,555,555 0% held
12 XENE XENON PHARMACEUTICALS INC Healthcare 3.1%$348.7m5,777,777 0% held
13 DFTX DEFINIUM THERAPEUTICS INC Healthcare 3.0%$338.2m7,188,888 44% added
14 UNIQURE NV 2.8%$309.9m6,727,777 13% added
15 VERA VERA THERAPEUTICS INC Healthcare 2.2%$245.6m5,723,888 -3% reduced
16 TSHA TAYSHA GENE THERAPIES INC Healthcare 1.5%$162.7m23,888,888 10% added
17 OCUL OCULAR THERAPEUTIX INC Healthcare 1.1%$123.1m12,540,000 2% added
18 DMRA DAMORA THERAPEUTICS INC Healthcare 0.9%$98.4m3,783,000 0% held
19 HEMAB THERAPEUTICS HLDGS INC 0.6%$70.7m1,925,150 new
20 GHRS GH RESEARCH PLC Healthcare 0.4%$48.4m1,800,000 0% held
21 VRDN VIRIDIAN THERAPEUTICS INC Healthcare 0.4%$45.9m2,500,000 67% added
22 SEPN SEPTERNA INC Healthcare 0.4%$44.8m1,337,500 0% held
23 AVTX AVALO THERAPEUTICS Healthcare 0.4%$43.1m2,333,333 65% added
24 FTH FAETH THERAPEUTICS INC 0.3%$36.1m1,444,039 new
25 WHWK WHITEHAWK THERAPEUTICS INC Healthcare 0.1%$13.1m2,849,402 0% held
26 LXEO LEXEO THERAPEUTICS INC Healthcare 0.1%$6.9m1,489,189 -21% reduced

What did Avoro Capital Advisors LLC sell? Positions exited since the previous filing

StockPrior weightPrior value
ASND ASCENDIS PHARMA45.8%$1.2bn
APLSUSD APELLIS PHARMACEUTICALS INC19.4%$491.7m
CNTA CENTESSA PHARMACEUTICALS PLC18.0%$454.0m
430 TERNS PHARMACEUTICALS INC11.9%$300.2m
SLNOEUR SOLENO THERAPEUTICS INC3.0%$77.0m
ALKS ALKERMES PLC1.7%$42.4m
MNKD MANNKIND CORP0.2%$5.4m

Sector mix

SectorWeight
Healthcare96.3%

Sectors cover positions whose ticker resolved to a sector; the remainder is unclassified, not cash.

Filing history

QuarterPositionsEquity value
Q2 202626$11.1bn
Q1 202630$10.2bn

How concentrated is Avoro Capital Advisors LLC's portfolio?

Across every quarter Avoro Capital Advisors LLC has filed, its median largest position is 14.4% of the book and its median top-ten weight is 78.0%, which WhaleCreep classifies as concentrated (the gate is a median largest position of 5%). Of 6.0 completed holding spells, the median lasted 1.0 quarters; 26.0 positions are still open and their final length is unknown.