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Soleus Capital Management, L.P.: 13F holdings, Q2 2026

Hedge fund · SEC EDGAR filings (CIK 1802630) · Explore on the interactive board

Soleus Capital Management, L.P. disclosed 97 US equity positions worth $2.9bn in its Q2 2026 13F filing (holdings as of June 30, 2026, filed August 11, 2026). Its largest position is KRYS at 12.0% of the reported book, followed by CELC, TGTX. The top ten holdings are 48.9% of the book, and the portfolio behaves like about 27 equal-weight positions. Versus the prior filing it opened 22 new positions, added to 25, reduced 41 and exited 18. Note: this manager's most recent filing is 3934 quarters behind the newest quarter on file, so these figures are history rather than current positioning.

This manager's most recent filing is 3934 quarter(s) behind the newest quarter on file. Treat these figures as history, not current positioning.
$2.9bnreported US equity book
97positions
12.0%largest position
48.9%top 10 weight
26.99effective positions (1/HHI)
2quarters on file since Q1 2026

What does Soleus Capital Management, L.P. own? Top holdings as of June 30, 2026

Change is measured in shares against the previous filing (Q1 2026), so price moves do not read as decisions. This quarter: 22 new, 25 added, 41 reduced, 18 exited.

#StockSectorWeightValueSharesΔ sharesAction
1 KRYS KRYSTAL BIOTECH INC Healthcare 12.0%$349.1m939,254 -19% reduced
2 CELC CELCUITY INC Healthcare 6.1%$178.3m1,704,318 33% added
3 TGTX TG THERAPEUTICS INC Healthcare 5.5%$160.9m2,927,895 -27% reduced
4 PODD INSULET CORP Healthcare 5.5%$159.7m1,049,000 86% added
5 NVCR NOVOCURE LTD Healthcare 5.2%$150.2m9,913,401 -6% reduced
6 UTHR UNITED THERAPEUTICS CORP DEL Healthcare 4.2%$122.2m225,587 21% added
7 INSP INSPIRE MED SYS INC Healthcare 3.0%$86.2m1,931,436 235% added
8 RIGL RIGEL PHARMACEUTICALS INC 2.5%$72.1m1,843,504 18335% added
9 ANIP ANI PHARMACEUTICALS INC Healthcare 2.5%$71.8m867,760 6% added
10 BBNX BETA BIONICS INC Healthcare 2.4%$68.8m4,393,714 1% added
11 VCEL VERICEL CORP Healthcare 2.2%$64.9m1,459,152 -43% reduced
12 PRAX PRAXIS PRECISION MEDICINES I Healthcare 2.0%$59.4m177,517 -46% reduced
13 GERN GERON CORP Healthcare 1.9%$54.8m42,808,659 3% added
14 ALKS ALKERMES PLC Healthcare 1.9%$53.9m1,029,252 -48% reduced
15 ERAS ERASCA INC Healthcare 1.7%$49.5m2,700,000 new
16 NPCE NEUROPACE INC 1.6%$46.3m2,911,122 -1% reduced
17 PGNY PROGYNY INC Healthcare 1.6%$46.2m1,602,000 -22% reduced
18 INDV INDIVIOR PHARMACEUTICALS INC Healthcare 1.5%$43.7m1,064,000 -16% reduced
19 PARABILIS MEDICINES INC 1.4%$40.1m1,465,070 new
20 EDAP TMS S A 1.3%$37.9m7,309,254 0% held
21 GMED GLOBUS MED INC Healthcare 1.3%$37.0m468,922 -36% reduced
22 RCUS ARCUS BIOSCIENCES INC Healthcare 1.2%$36.0m1,168,738 159% added
23 SNDX SYNDAX PHARMACEUTICALS INC Healthcare 1.2%$35.6m1,628,039 -6% reduced
24 NRIX NURIX THERAPEUTICS INC Healthcare 1.2%$35.5m1,465,163 56% added
25 LEGN LEGEND BIOTECH CORP Healthcare 1.2%$34.8m1,205,000 new
26 JBIO JADE BIOSCIENCES INC Healthcare 1.2%$34.5m1,550,690 95% added
27 UNH UNITEDHEALTH GROUP INC Healthcare 1.1%$33.3m80,000 new
28 AVTX AVALO THERAPEUTICS INC Healthcare 1.1%$30.6m1,654,978 274% added
29 URGN UROGEN PHARMA LTD Healthcare 1.1%$30.5m829,810 14% added
30 MBX MBX BIOSCIENCES INC Healthcare 1.0%$28.4m515,279 188% added
31 PALI PALISADE BIO INC Healthcare 0.9%$27.3m13,063,687 new
32 PHVS PHARVARIS N V Healthcare 0.9%$25.3m730,907 4% added
33 ORGO ORGANOGENESIS HLDGS INC Healthcare 0.8%$24.6m10,140,951 1% added
34 SUPN SUPERNUS PHARMACEUTICALS Healthcare 0.8%$24.2m520,000 new
35 PRCT PROCEPT BIOROBOTICS CORP Healthcare 0.8%$22.6m1,003,000 527% added
36 TNGX TANGO THERAPEUTICS INC Healthcare 0.8%$22.2m709,000 58% added
37 IKT INHIBIKASE THERAPEUTICS INC 0.8%$22.1m10,875,000 0% held
38 TRVI TREVI THERAPEUTICS INC Healthcare 0.8%$22.0m1,179,618 -27% reduced
39 BMRN BIOMARIN PHARMACEUTICAL INC Healthcare 0.7%$21.5m375,572 -42% reduced
40 LIVN LIVANOVA PLC Healthcare 0.7%$21.0m254,957 -56% reduced
41 ARGX ARGENX SE Healthcare 0.6%$18.5m19,955 470% added
42 NVCT NUVECTIS PHARMA INC 0.6%$18.4m1,000,000 new
43 CAPR CAPRICOR THERAPEUTICS INC Healthcare 0.6%$18.3m761,737 new
44 EWTX EDGEWISE THERAPEUTICS INC Healthcare 0.6%$18.3m450,889 -69% reduced
45 PRLD PRELUDE THERAPEUTICS INC 0.6%$18.0m3,378,378 new
46 XENE XENON PHARMACEUTICALS INC Healthcare 0.6%$16.1m267,000 -9% reduced
47 CCCC C4 THERAPEUTICS INC Healthcare 0.5%$15.8m3,377,981 -11% reduced
48 KINIKSA PHARMACEUTICALS INTL 0.5%$15.8m246,353 -53% reduced
49 KIDS ORTHOPEDIATRICS CORP Healthcare 0.5%$14.0m732,144 19% added
50 AVALYN PHARMACEUTICALS INC 0.5%$13.8m419,000 new

What did Soleus Capital Management, L.P. sell? Positions exited since the previous filing

StockPrior weightPrior value
PCVX VAXCYTE INC24.2%$22.4m
ICLR ICON PLC23.0%$21.2m
TVTX TRAVERE THERAPEUTICS INC17.5%$16.2m
INBX INHIBRX BIOSCIENCES INC9.5%$8.8m
DXCM DEXCOM INC9.5%$8.8m
IMUX IMMUNIC INC5.4%$5.0m
ETON ETON PHARMACEUTICALS INC4.4%$4.1m
ARWR ARROWHEAD PHARMACEUTICALS IN1.9%$1.8m
CTMX CYTOMX THERAPEUTICS INC.1.5%$1.4m
COGT COGENT BIOSCIENCES INC0.4%$384.9k
TYRA TYRA BIOSCIENCES INC0.4%$383.0k
STAA STAAR SURGICAL CO0.4%$374.0k
ANAB ANAPTYSBIO INC0.4%$332.8k
RAPP RAPPORT THERAPEUTICS INC0.3%$312.9k
ZYME ZYMEWORKS INC0.3%$250.4k
LB PHARMACEUTICALS INC0.3%$246.6k
ORKA ORUKA THERAPEUTICS INC0.3%$245.2k
JSPR JASPER THERAPEUTICS INC0.3%$242.1k

Sector mix

SectorWeight
Healthcare88.3%

Sectors cover positions whose ticker resolved to a sector; the remainder is unclassified, not cash.

Filing history

QuarterPositionsEquity value
Q2 202697$2.9bn
Q1 202693$2.5bn

How concentrated is Soleus Capital Management, L.P.'s portfolio?

Across every quarter Soleus Capital Management, L.P. has filed, its median largest position is 12.0% of the book and its median top-ten weight is 49.6%, which WhaleCreep classifies as concentrated (the gate is a median largest position of 5%). Of 17.0 completed holding spells, the median lasted 1.0 quarters; 97.0 positions are still open and their final length is unknown.