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Vestal Point Capital, LP 13F holdings, Q1 2025

Holdings as of March 31, 2025 · filings on SEC EDGAR · latest filing →

Vestal Point Capital, LP disclosed 63 US equity positions worth $1.4bn in its Q1 2025 13F filing. The largest position was ACLXGBX at 11.2% of the reported book, followed by CYTK and INSM. Against the Q4 2024 filing, it opened 10 new positions, added to 24 and reduced 10 among the top 50 holdings.

← Q4 2024 · Q2 2025 →

What did Vestal Point Capital, LP own in Q1 2025? Top 50 positions

#StockSectorWeightValueSharesΔ sharesvs Q4 2024
1 ACLXGBX Arcellx Inc 11.2%$156.6m2,387,720 403% added
2 CYTK Cytokinetics Inc Healthcare 7.4%$104.1m2,590,531 10% added
3 INSM Insmed Inc Healthcare 5.9%$82.0m1,075,000 19% added
4 Nuvalent Inc 5.4%$76.2m1,075,000 79% added
5 VERA Vera Therapeutics Inc Healthcare 4.3%$60.0m2,500,000 133% added
6 4XC1 KalVista Pharmaceuticals Inc 3.9%$54.8m4,751,292 -0% held
7 QURE uniQure NV 3.6%$50.8m4,792,572 58% added
8 CRNXGBP Crinetics Pharmaceuticals Inc 3.6%$50.3m1,500,000 – new
9 XENE Xenon Pharmaceuticals Inc Healthcare 3.1%$43.6m1,300,000 60% added
10 SRRK Scholar Rock Holding Corp Healthcare 3.0%$41.8m1,300,000 – new
11 BCAX Bicara Therapeutics Inc 2.6%$36.1m2,768,975 290% added
12 GERN Geron Corp Healthcare 2.5%$35.0m22,005,340 100% added
13 AM6 Amicus Therapeutics Inc 2.5%$34.9m4,275,000 28% added
14 IMTX Immatics NV Healthcare 2.3%$32.4m7,192,700 15% added
15 GPCR Structure Therapeutics Inc Healthcare 2.2%$31.0m1,788,990 4% added
16 DNTH Dianthus Therapeutics Inc Healthcare 2.2%$30.8m1,700,069 58% added
17 SVRA Savara Inc Healthcare 2.2%$30.5m11,000,000 2% added
18 TYRA Tyra Biosciences Inc Healthcare 1.9%$26.8m2,879,829 191% added
19 DHR Danaher Corporation Healthcare 1.8%$25.6m125,000 – new
20 URGN UroGen Pharma Ltd Healthcare 1.7%$23.8m2,152,957 32% added
21 ASND Ascendis Pharma A/S Healthcare 1.7%$23.4m150,142 -71% reduced
22 CATBUSD Astria Therapeutics Inc 1.6%$22.3m4,180,000 0% held
23 DAWNGBX Day One Biopharmaceuticals Inc 1.5%$20.6m2,598,127 80% added
24 DYN Dyne Therapeutics Inc Healthcare 1.3%$18.8m1,800,000 – new
25 RARE Ultragenyx Pharmaceutical Inc Healthcare 1.3%$18.1m500,000 -67% reduced
26 LQDA Liquidia Corp Healthcare 1.3%$18.1m1,227,403 -30% reduced
27 COGT Cogent Biosciences Inc Healthcare 1.3%$18.0m3,000,000 – new
28 ESTA Establishment Labs Holdings In Healthcare 1.3%$17.7m433,193 44% added
29 VRNA Verona Pharma PLC 1.2%$17.0m267,627 -46% reduced
30 PRGO Perrigo Co PLC Healthcare 1.2%$16.5m587,649 57% added
31 GEHC GE HealthCare Technologies Inc Healthcare 1.2%$16.5m204,130 – new
32 Nyxoah SA 1.2%$16.2m2,318,954 -21% reduced
33 GMED Globus Medical Inc Healthcare 1.0%$14.6m200,000 -38% reduced
34 NRIX Nurix Therapeutics Inc Healthcare 1.0%$13.4m1,125,552 132% added
35 SRPT Sarepta Therapeutics Inc Healthcare 0.9%$12.8m200,000 -20% reduced
36 BRKR Bruker Corp Healthcare 0.9%$12.5m300,000 – new
37 CDTX Cidara Therapeutics Inc 0.8%$10.9m504,542 – new
38 BDTX Black Diamond Therapeutics Inc 0.6%$8.7m5,600,000 0% held
39 MLTX MoonLake Immunotherapeutics Healthcare 0.6%$7.8m200,000 – new
40 SLDB Solid Biosciences Inc Healthcare 0.5%$6.5m1,753,558 -38% reduced
41 IMVT Immunovant Inc Healthcare 0.4%$6.0m350,000 678% added
42 ZYME Zymeworks Inc Healthcare 0.4%$6.0m500,000 170% added
43 APLT Applied Therapeutics Inc 0.4%$5.6m11,500,000 0% held
44 2662247D iTeos Therapeutics Inc 0.4%$5.4m900,000 0% held
45 LKFT Galapagos NV Healthcare 0.4%$5.0m200,000 11% added
46 VYGR Voyager Therapeutics Inc Healthcare 0.3%$4.2m1,249,418 2% added
47 LXEO Lexeo Therapeutics Inc Healthcare 0.3%$3.9m1,136,249 -5% reduced
48 Kiniksa Pharmaceuticals Intl 0.3%$3.8m169,864 – new
49 CLDX Celldex Therapeutics Inc Healthcare 0.3%$3.6m198,646 -35% reduced
50 OKUR OnKure Therapeutics Inc 0.2%$2.7m635,000 0% held

Weights are shares of the reported long US equity book (options excluded). Values are as filed, normalised to whole dollars. Share changes compare against the immediately preceding filing only.