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Casdin Capital 13F holdings, Q1 2025

Holdings as of March 31, 2025 · filings on SEC EDGAR · latest filing →

Casdin Capital disclosed 44 US equity positions worth $1.2bn in its Q1 2025 13F filing. The largest position was WGS at 25.4% of the reported book, followed by BLFS and RVMD. Against the Q4 2024 filing, it opened 8 new positions, added to 5 and reduced 9 among the top 44 holdings.

← Q4 2024 · Q2 2025 →

What did Casdin Capital own in Q1 2025? Top 44 positions

#StockSectorWeightValueSharesΔ sharesvs Q4 2024
1 WGS GENEDX HOLDINGS CORP Healthcare 25.4%$310.6m3,507,164 0% held
2 BLFS BIOLIFE SOLUTIONS INC Healthcare 16.3%$198.9m8,707,165 0% held
3 RVMD REVOLUTION MEDICINES INC Healthcare 10.7%$130.8m3,697,933 -0% held
4 LAB STANDARD BIOTOOLS INC Healthcare 6.7%$82.2m76,075,636 7% added
5 AVIDITY BIOSCIENCES INC 4.9%$60.4m2,045,000 0% held
6 SRPT SAREPTA THERAPEUTICS INC Healthcare 4.7%$57.5m900,783 -16% reduced
7 ILMN ILLUMINA INC Healthcare 3.9%$47.2m595,000 -21% reduced
8 ALNY ALNYLAM PHARMACEUTICALS INC Healthcare 2.6%$32.4m120,000 -14% reduced
9 2655787D BLUEPRINT MEDICINES CORP 2.4%$28.9m326,378 0% held
10 BEAM BEAM THERAPEUTICS INC Healthcare 2.3%$27.8m1,425,562 14% added
11 RLAY RELAY THERAPEUTICS INC Healthcare 1.9%$23.8m9,098,574 2% added
12 CDXS CODEXIS INC Healthcare 1.8%$21.8m8,100,000 0% held
13 VERVE THERAPEUTICS INC 1.5%$18.3m3,995,571 0% held
14 EXK EXACT SCIENCES CORP Basic Materials 1.4%$17.5m405,000 -38% reduced
15 NGNE NEUROGENE INC 1.2%$15.2m1,295,361 0% held
16 NTLA INTELLIA THERAPEUTICS INC Healthcare 1.2%$14.2m2,000,000 0% held
17 DNLI DENALI THERAPEUTICS INC Healthcare 1.1%$13.5m990,000 0% held
18 GPCR STRUCTURE THERAPEUTICS INC Healthcare 1.0%$12.1m700,000 0% held
19 ONC BEIGENE LTD Healthcare 0.9%$10.9m40,000 new
20 GH GUARDANT HEALTH INC Healthcare 0.9%$10.7m250,000 -29% reduced
21 MAZE MAZE THERAPEUTICS INC 0.9%$10.4m946,357 new
22 2SEVENTY BIO INC 0.8%$9.9m2,000,000 0% held
23 VCYT VERACYTE INC Healthcare 0.7%$8.2m276,308 0% held
24 GEHC GE HEALTHCARE TECHNOLOGIES I Healthcare 0.7%$8.1m100,000 new
25 SNDX SYNDAX PHARMACEUTICALS INC Healthcare 0.6%$7.8m635,000 34% added
26 AGIO AGIOS PHARMACEUTICALS INC Healthcare 0.6%$7.3m250,000 0% held
27 MRNA MODERNA INC Healthcare 0.5%$6.4m225,000 29% added
28 HIMS HIMS & HERS HEALTH INC Healthcare 0.5%$5.9m200,000 new
29 TNYA TENAYA THERAPEUTICS INC 0.3%$3.8m6,732,971 0% held
30 VSTM VERASTEM INC Healthcare 0.3%$3.6m600,000 new
31 SEPN SEPTERNA INC 0.3%$3.2m553,268 0% held
32 SLDB SOLID BIOSCIENCES INC Healthcare 0.2%$2.9m775,000 new
33 ABSI ABSCI CORPORATION 0.2%$2.4m973,260 0% held
34 TDOC TELADOC HEALTH INC Healthcare 0.2%$2.4m300,000 new
35 IPSC CENTURY THERAPEUTICS INC Healthcare 0.1%$1.5m3,212,316 -38% reduced
36 DYN DYNE THERAPEUTICS INC Healthcare 0.1%$1.0m100,000 new
37 CTNM CONTINEUM THERAPEUTICS INC 0.1%$1.0m148,333 -50% reduced
38 RXRX RECURSION PHARMACEUTICALS IN Healthcare 0.1%$874.6k165,323 0% held
39 PACB PACIFIC BIOSCIENCES CALIF IN Healthcare 0.1%$854.0k723,767 -30% reduced
40 PRME PRIME MEDICINE INC 0.1%$730.7k367,175 0% held
41 GLUE MONTE ROSA THERAPEUTICS INC 0.0%$399.1k86,014 0% held
42 GINKGO BIOWORKS HOLDINGS INC 0.0%$208.0k36,493 0% held
43 TNGX TANGO THERAPEUTICS INC Healthcare 0.0%$171.2k125,000 -89% reduced
44 KRONOS BIO INC 0.0%$102.2k123,839 0% held

Weights are shares of the reported long US equity book (options excluded). Values are as filed, normalised to whole dollars. Share changes compare against the immediately preceding filing only.