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Casdin Capital 13F holdings, Q4 2024

Holdings as of December 31, 2024 · filings on SEC EDGAR · latest filing →

Casdin Capital disclosed 38 US equity positions worth $1.5bn in its Q4 2024 13F filing. The largest position was WGS at 18.0% of the reported book, followed by BLFS and RVMD. Against the Q3 2024 filing, it opened 5 new positions, added to 3 and reduced 5 among the top 38 holdings.

← Q3 2024 · Q1 2025 →

What did Casdin Capital own in Q4 2024? Top 38 positions

#StockSectorWeightValueSharesΔ sharesvs Q3 2024
1 WGS GENEDX HOLDINGS CORP Healthcare 18.0%$269.6m3,507,164 0% held
2 BLFS BIOLIFE SOLUTIONS INC Healthcare 15.1%$226.0m8,707,165 0% held
3 RVMD REVOLUTION MEDICINES INC Healthcare 10.8%$161.8m3,699,283 -10% reduced
4 SRPT SAREPTA THERAPEUTICS INC Healthcare 8.7%$130.5m1,073,500 0% held
5 LAB STANDARD BIOTOOLS INC Healthcare 8.3%$124.7m71,254,677 0% held
6 ILMN ILLUMINA INC Healthcare 6.7%$100.2m750,000 0% held
7 AVIDITY BIOSCIENCES INC 4.0%$59.5m2,045,000 -2% reduced
8 CDXS CODEXIS INC Healthcare 2.6%$38.6m8,100,000 0% held
9 RLAY RELAY THERAPEUTICS INC Healthcare 2.5%$36.9m8,948,574 -3% reduced
10 EXK EXACT SCIENCES CORP Basic Materials 2.4%$36.5m650,000 0% held
11 ALNY ALNYLAM PHARMACEUTICALS INC Healthcare 2.2%$32.9m140,000 -18% reduced
12 BEAM BEAM THERAPEUTICS INC Healthcare 2.1%$31.0m1,250,000 61% added
13 NGNE NEUROGENE INC 2.0%$29.6m1,295,361 147% added
14 2655787D BLUEPRINT MEDICINES CORP 1.9%$28.5m326,378 0% held
15 NTLA INTELLIA THERAPEUTICS INC Healthcare 1.6%$23.3m2,000,000 0% held
16 VERVE THERAPEUTICS INC 1.5%$22.5m3,995,571 0% held
17 DNLI DENALI THERAPEUTICS INC Healthcare 1.3%$20.2m990,000 0% held
18 GPCR STRUCTURE THERAPEUTICS INC Healthcare 1.3%$19.0m700,000 0% held
19 SEPN SEPTERNA INC 0.8%$12.7m553,268 new
20 VCYT VERACYTE INC Healthcare 0.7%$10.9m276,308 -59% reduced
21 GH GUARDANT HEALTH INC Healthcare 0.7%$10.7m350,000 0% held
22 TNYA TENAYA THERAPEUTICS INC 0.6%$9.6m6,732,971 0% held
23 AGIO AGIOS PHARMACEUTICALS INC Healthcare 0.5%$8.2m250,000 new
24 MRNA MODERNA INC Healthcare 0.5%$7.3m175,000 new
25 4D MOLECULAR THERAPEUTICS IN 0.4%$6.4m1,150,000 0% held
26 SNDX SYNDAX PHARMACEUTICALS INC Healthcare 0.4%$6.3m475,000 0% held
27 2SEVENTY BIO INC 0.4%$5.9m2,000,000 0% held
28 IPSC CENTURY THERAPEUTICS INC Healthcare 0.4%$5.2m5,190,506 62% added
29 FTRE FORTREA HLDGS INC Healthcare 0.3%$5.1m275,000 new
30 CTNM CONTINEUM THERAPEUTICS INC 0.3%$4.3m296,666 0% held
31 TNGX TANGO THERAPEUTICS INC Healthcare 0.2%$3.7m1,188,349 0% held
32 ABSI ABSCI CORPORATION 0.2%$2.5m973,260 0% held
33 PACB PACIFIC BIOSCIENCES CALIF IN Healthcare 0.1%$1.9m1,035,859 0% held
34 RXRX RECURSION PHARMACEUTICALS IN Healthcare 0.1%$1.1m165,323 new
35 PRME PRIME MEDICINE INC 0.1%$1.1m367,175 0% held
36 GLUE MONTE ROSA THERAPEUTICS INC 0.0%$596.9k86,014 0% held
37 GINKGO BIOWORKS HOLDINGS INC 0.0%$358.4k36,493 0% held
38 KRONOS BIO INC 0.0%$117.6k123,839 0% held

Weights are shares of the reported long US equity book (options excluded). Values are as filed, normalised to whole dollars. Share changes compare against the immediately preceding filing only.