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Rock Springs Capital Management LP: 13F holdings, Q2 2026

Hedge fund · SEC EDGAR filings (CIK 1595725) · Explore on the interactive board

Rock Springs Capital Management LP disclosed 104 US equity positions worth $2.0bn in its Q2 2026 13F filing (holdings as of June 30, 2026, filed August 14, 2026). Its largest position is RVMD at 10.1% of the reported book, followed by TVTX, LLY. The top ten holdings are 44.0% of the book, and the portfolio behaves like about 33 equal-weight positions. Versus the prior filing it opened 17 new positions, added to 35, reduced 30 and exited 13. Note: this manager's most recent filing is 3934 quarters behind the newest quarter on file, so these figures are history rather than current positioning.

This manager's most recent filing is 3934 quarter(s) behind the newest quarter on file. Treat these figures as history, not current positioning.
$2.0bnreported US equity book
104positions
10.1%largest position
44.0%top 10 weight
32.75effective positions (1/HHI)
2quarters on file since Q1 2026

What does Rock Springs Capital Management LP own? Top holdings as of June 30, 2026

Change is measured in shares against the previous filing (Q1 2026), so price moves do not read as decisions. This quarter: 17 new, 35 added, 30 reduced, 13 exited.

#StockSectorWeightValueSharesΔ sharesAction
1 RVMD REVOLUTION MEDICINES INC Healthcare 10.1%$207.0m1,105,210 -9% reduced
2 TVTX TRAVERE THERAPEUTICS INC Healthcare 6.0%$123.8m2,179,069 47% added
3 LLY ELI LILLY & CO Healthcare 5.8%$118.4m98,700 0% held
4 MDGL MADRIGAL PHARMACEUTICALS INC Healthcare 4.6%$94.0m174,999 2% added
5 MIRM MIRUM PHARMACEUTICALS INC Healthcare 4.6%$93.4m798,145 -2% reduced
6 RYTM RHYTHM PHARMACEUTICALS INC Healthcare 3.8%$76.9m692,598 0% held
7 KYMR KYMERA THERAPEUTICS INC Healthcare 2.5%$52.0m453,156 -9% reduced
8 ARGX ARGENX SE Healthcare 2.4%$48.9m52,750 -46% reduced
9 ASND ASCENDIS PHARMA A/S Healthcare 2.2%$45.0m168,750 new
10 XENE XENON PHARMACEUTICALS INC Healthcare 2.0%$41.3m683,907 -10% reduced
11 SRRK SCHOLAR ROCK HLDG CORP Healthcare 1.9%$39.3m715,452 -3% reduced
12 INSM INSMED INC Healthcare 1.9%$38.6m362,150 15% added
13 PEN PENUMBRA INC Healthcare 1.8%$36.5m115,750 -4% reduced
14 GPCR STRUCTURE THERAPEUTICS INC Healthcare 1.7%$34.4m640,317 0% held
15 RARE ULTRAGENYX PHARMACEUTICAL IN Healthcare 1.6%$32.3m967,855 -21% reduced
16 IRTC IRHYTHM HOLDINGS INC Healthcare 1.6%$32.1m269,650 3% added
17 ISRG INTUITIVE SURGICAL INC Healthcare 1.5%$30.4m76,460 -7% reduced
18 AGL AGILON HEALTH INC 1.4%$28.1m262,600 1% added
19 UNH UNITEDHEALTH GROUP INC Healthcare 1.3%$26.5m63,750 20% added
20 CLDX CELLDEX THERAPEUTICS INC NEW Healthcare 1.3%$26.0m699,146 8% added
21 ERAS ERASCA INC Healthcare 1.3%$25.7m1,402,150 27% added
22 NBIX NEUROCRINE BIOSCIENCES INC Healthcare 1.2%$24.4m144,750 -4% reduced
23 ELVN ENLIVEN THERAPEUTICS INC Healthcare 1.2%$23.6m464,625 -44% reduced
24 THC TENET HEALTHCARE CORP Healthcare 1.1%$23.4m125,000 0% held
25 DXCM DEXCOM INC Healthcare 1.1%$23.1m343,000 -4% reduced
26 ACRS ACLARIS THERAPEUTICS INC Healthcare 1.1%$22.9m4,330,532 -3% reduced
27 MMED MINIMED GROUP INC 1.1%$22.7m1,520,000 44% added
28 BSX BOSTON SCIENTIFIC CORP Healthcare 1.1%$22.6m528,500 3% added
29 PHVS PHARVARIS N V Healthcare 1.1%$22.4m648,333 0% held
30 AVALYN PHARMACEUTICALS INC 1.1%$21.8m662,918 new
31 HEMAB THERAPEUTICS HLDGS INC 1.0%$21.1m575,432 new
32 DYN DYNE THERAPEUTICS INC Healthcare 1.0%$20.9m942,154 -3% reduced
33 ALNY ALNYLAM PHARMACEUTICALS INC Healthcare 1.0%$20.1m66,750 -10% reduced
34 COGT COGENT BIOSCIENCES INC Healthcare 1.0%$20.0m515,917 -17% reduced
35 AGIO AGIOS PHARMACEUTICALS INC Healthcare 1.0%$19.8m532,563 -33% reduced
36 NEWAMSTERDAM PHARMA COMPANY 1.0%$19.7m582,744 -1% reduced
37 VERA VERA THERAPEUTICS INC Healthcare 0.9%$18.3m427,584 -15% reduced
38 TARS TARSUS PHARMACEUTICALS INC Healthcare 0.9%$17.4m277,087 23% added
39 HTFL HEARTFLOW INC Healthcare 0.8%$16.8m573,500 0% held
40 MBX MBX BIOSCIENCES INC Healthcare 0.8%$16.5m298,218 4% added
41 CYTK CYTOKINETICS INC Healthcare 0.8%$16.0m187,980 314% added
42 BCAX BICARA THERAPEUTICS INC Healthcare 0.8%$15.9m535,286 9% added
43 PARABILIS MEDICINES INC 0.8%$15.8m578,028 new
44 ZLAB ZAI LAB LTD Healthcare 0.8%$15.5m814,707 0% held
45 DHR DANAHER CORP DEL Healthcare 0.7%$14.5m76,300 24% added
46 TNGX TANGO THERAPEUTICS INC Healthcare 0.7%$14.3m456,551 18% added
47 EVH EVOLENT HEALTH INC Healthcare 0.7%$13.6m2,500,000 -7% reduced
48 PTCT PTC THERAPEUTICS INC Healthcare 0.6%$13.2m162,298 0% held
49 MLYS MINERALYS THERAPEUTICS INC Healthcare 0.6%$13.1m484,951 10% added
50 ZBIO ZENAS BIOPHARMA INC 0.6%$12.7m502,077 0% held

What did Rock Springs Capital Management LP sell? Positions exited since the previous filing

StockPrior weightPrior value
ASND ASCENDIS PHARMA A/S38.0%$44.4m
ACLXGBX ARCELLX INC16.7%$19.5m
CNTA CENTESSA PHARMACEUTICALS PLC12.0%$14.0m
SLNOEUR SOLENO THERAPEUTICS INC7.4%$8.6m
REGN REGENERON PHARMACEUTICALS6.7%$7.8m
APLSUSD APELLIS PHARMACEUTICALS INC5.6%$6.5m
430 TERNS PHARMACEUTICALS INC5.1%$6.0m
XBI SPDR SERIES TRUST3.3%$3.8m
EW EDWARDS LIFESCIENCES CORP2.0%$2.3m
ACHC ACADIA HEALTHCARE COMPANY IN1.5%$1.8m
JAZZ JAZZ PHARMACEUTICALS PLC0.9%$1.1m
GOSS GOSSAMER BIO INC0.5%$528.7k
AM6 AMICUS THERAPEUTIC0.3%$304.6k

Sector mix

SectorWeight
Healthcare91.2%

Sectors cover positions whose ticker resolved to a sector; the remainder is unclassified, not cash.

Filing history

QuarterPositionsEquity value
Q2 2026104$2.0bn
Q1 2026100$1.7bn

How concentrated is Rock Springs Capital Management LP's portfolio?

Across every quarter Rock Springs Capital Management LP has filed, its median largest position is 8.5% of the book and its median top-ten weight is 42.3%, which WhaleCreep classifies as concentrated (the gate is a median largest position of 5%). Of 12.0 completed holding spells, the median lasted 1.0 quarters; 104.0 positions are still open and their final length is unknown.