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Vestal Point Capital, LP 13F holdings, Q4 2024

Holdings as of December 31, 2024 · filings on SEC EDGAR · latest filing →

Vestal Point Capital, LP disclosed 73 US equity positions worth $1.7bn in its Q4 2024 13F filing. The largest position was JAZZ at 7.1% of the reported book, followed by CYTK and MRK. Against the Q3 2024 filing, it opened 16 new positions, added to 27 and reduced 7 among the top 50 holdings.

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What did Vestal Point Capital, LP own in Q4 2024? Top 50 positions

#StockSectorWeightValueSharesΔ sharesvs Q3 2024
1 JAZZ Jazz Pharmaceuticals PLC Healthcare 7.1%$120.1m975,000 8% added
2 CYTK Cytokinetics Inc Healthcare 6.6%$110.5m2,350,000 57% added
3 MRK Merck & Co Inc Healthcare 4.7%$79.6m800,000 – new
4 ASND Ascendis Pharma A/S Healthcare 4.2%$71.6m520,000 108% added
5 RARE Ultragenyx Pharmaceutical Inc Healthcare 3.7%$63.1m1,500,000 100% added
6 INSM Insmed Inc Healthcare 3.7%$62.1m900,000 -44% reduced
7 BMRN BioMarin Pharmaceutical Inc Healthcare 3.4%$56.5m860,000 115% added
8 QURE uniQure NV 3.2%$53.4m3,025,000 -36% reduced
9 SLNOEUR Soleno Therapeutics Inc 2.8%$47.6m1,060,000 47% added
10 Nuvalent Inc 2.8%$47.0m600,000 – new
11 GPCR Structure Therapeutics Inc Healthcare 2.8%$46.8m1,725,000 50% added
12 VERA Vera Therapeutics Inc Healthcare 2.7%$45.5m1,075,000 – new
13 IMTX Immatics NV Healthcare 2.6%$44.6m6,275,000 67% added
14 4XC1 KalVista Pharmaceuticals Inc 2.4%$40.4m4,770,000 19% added
15 GERN Geron Corp Healthcare 2.3%$38.9m11,000,000 948% added
16 CATBUSD Astria Therapeutics Inc 2.2%$37.4m4,180,000 4% added
17 ACLXGBX Arcellx Inc 2.2%$36.4m475,000 -30% reduced
18 SNY Sanofi SA 2.1%$36.2m750,000 400% added
19 GSK GSK PLC Healthcare 2.0%$33.8m1,000,000 233% added
20 SVRA Savara Inc Healthcare 2.0%$33.1m10,775,000 33% added
21 XENE Xenon Pharmaceuticals Inc Healthcare 1.9%$31.8m810,000 -2% reduced
22 AM6 Amicus Therapeutics Inc 1.9%$31.6m3,350,000 – new
23 AZN AstraZeneca PLC Healthcare 1.8%$31.1m475,000 – new
24 SRPT Sarepta Therapeutics Inc Healthcare 1.8%$30.4m250,000 – new
25 MDGL Madrigal Pharmaceuticals Inc Healthcare 1.7%$29.3m95,000 217% added
26 GMED Globus Medical Inc Healthcare 1.6%$26.9m325,000 – new
27 DNTH Dianthus Therapeutics Inc Healthcare 1.4%$23.4m1,075,000 172% added
28 Nyxoah SA 1.4%$23.4m2,924,216 – new
29 VRNA Verona Pharma PLC 1.4%$23.0m495,000 – new
30 IONS Ionis Pharmaceuticals Inc Healthcare 1.2%$20.8m595,000 – new
31 LQDA Liquidia Corp Healthcare 1.2%$20.7m1,760,000 17% added
32 DAWNGBX Day One Biopharmaceuticals Inc 1.1%$18.2m1,440,000 -42% reduced
33 URGN UroGen Pharma Ltd Healthcare 1.0%$17.4m1,630,000 308% added
34 LEGN Legend Biotech Corp Healthcare 0.9%$15.5m475,000 280% added
35 ROIV Roivant Sciences Ltd Healthcare 0.9%$14.8m1,250,000 – new
36 REGN Regeneron Pharmaceuticals Inc Healthcare 0.8%$14.2m20,000 – new
37 ESTA Establishment Labs Holdings In Healthcare 0.8%$13.8m300,000 650% added
38 TYRA Tyra Biosciences Inc Healthcare 0.8%$13.8m990,000 – new
39 BCAX Bicara Therapeutics Inc 0.7%$12.4m710,000 67% added
40 BDTX Black Diamond Therapeutics Inc 0.7%$12.0m5,600,000 11% added
41 SLDB Solid Biosciences Inc Healthcare 0.7%$11.4m2,850,000 2% added
42 A Agilent Technologies Inc Healthcare 0.6%$10.1m75,000 -25% reduced
43 APLT Applied Therapeutics Inc 0.6%$9.8m11,500,000 904% added
44 PRGO Perrigo Co PLC Healthcare 0.6%$9.6m375,000 – new
45 NRIX Nurix Therapeutics Inc Healthcare 0.5%$9.1m485,000 14% added
46 LXEO Lexeo Therapeutics Inc Healthcare 0.5%$7.9m1,200,000 41% added
47 ZLAB Zai Lab Ltd Healthcare 0.5%$7.9m300,000 – new
48 CLDX Celldex Therapeutics Inc Healthcare 0.5%$7.7m305,000 – new
49 VYGR Voyager Therapeutics Inc Healthcare 0.4%$7.0m1,230,000 151% added
50 2662247D iTeos Therapeutics Inc 0.4%$6.9m900,000 -12% reduced

Weights are shares of the reported long US equity book (options excluded). Values are as filed, normalised to whole dollars. Share changes compare against the immediately preceding filing only.