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Boxer Capital Management, LLC 13F holdings, Q3 2025

Holdings as of September 30, 2025 · filings on SEC EDGAR · latest filing →

Boxer Capital Management, LLC disclosed 34 US equity positions worth $313.7m in its Q3 2025 13F filing. The largest position was TNGX at 26.2% of the reported book, followed by QURE and RVMD. Against the Q2 2025 filing, it opened 15 new positions, added to 2 and reduced 9 among the top 34 holdings.

← Q2 2025 · Q4 2025 →

What did Boxer Capital Management, LLC own in Q3 2025? Top 34 positions

#StockSectorWeightValueSharesΔ sharesvs Q2 2025
1 TNGX TANGO THERAPEUTICS INC Healthcare 26.2%$82.1m9,771,485 0% held
2 QURE UNIQURE NV 14.9%$46.7m800,000 -11% reduced
3 RVMD REVOLUTION MEDICINES INC Healthcare 6.0%$18.7m400,000 -50% reduced
4 KYMR KYMERA THERAPEUTICS INC Healthcare 5.8%$18.1m319,100 -26% reduced
5 KOD KODIAK SCIENCES INC Healthcare 3.9%$12.3m750,000 0% held
6 PTCT PTC THERAPEUTICS INC Healthcare 3.9%$12.3m200,000 – new
7 AMLX AMYLYX PHARMACEUTICALS INC Healthcare 3.9%$12.2m900,000 -27% reduced
8 URGN UROGEN PHARMA LTD Healthcare 3.7%$11.5m575,000 0% held
9 MERUS N V 3.6%$11.3m120,000 -67% reduced
10 CYTK CYTOKINETICS INC Healthcare 3.5%$11.0m200,000 – new
11 ABVX ABIVAX SA 3.2%$10.2m120,000 – new
12 PTGX PROTAGONIST THERAPEUTICS INC Healthcare 2.3%$7.3m110,000 83% added
13 NKTR NEKTAR THERAPEUTICS Healthcare 2.3%$7.1m125,000 0% held
14 CBIO CRESCENT BIOPHARMA INC. 1.7%$5.4m453,686 0% held
15 INO INOVIO PHARMACEUTICALS INC 1.7%$5.4m2,300,000 – new
16 SRPT SAREPTA THERAPEUTICS INC Healthcare 1.5%$4.8m250,000 900% added
17 CDTX CIDARA THERAPEUTICS INC 1.5%$4.6m48,000 -13% reduced
18 CELC CELCUITY INC Healthcare 1.4%$4.4m90,000 – new
19 REPL REPLIMUNE GROUP INC Healthcare 1.4%$4.4m1,050,000 -53% reduced
20 SLDB SOLID BIOSCIENCES INC Healthcare 1.2%$3.7m600,000 – new
21 DNLI DENALI THERAPEUTICS INC Healthcare 1.2%$3.6m250,000 – new
22 PGEN PRECIGEN INC Healthcare 0.9%$2.8m850,000 – new
23 APGE APOGEE THERAPEUTICS INC Healthcare 0.6%$2.0m50,000 – new
24 BRD1EUR MIND MEDICINE MINDMED INC 0.6%$1.9m163,500 – new
25 MLTX MOONLAKE IMMUNOTHERAPEUTICS Healthcare 0.6%$1.8m250,000 – new
26 NRIX NURIX THERAPEUTICS INC Healthcare 0.5%$1.6m175,000 0% held
27 AVTX AVALO THERAPEUTICS INC Healthcare 0.5%$1.6m125,000 – new
28 MIST MILESTONE PHARMACEUTICALS IN 0.4%$1.3m666,666 – new
29 PEPG PEPGEN INC Healthcare 0.4%$1.2m250,000 – new
30 LB PHARMACEUTICALS INC 0.4%$1.1m70,000 – new
31 TIL INSTIL BIO INC 0.3%$1.1m60,700 -14% reduced
32 4XC1 KALVISTA PHARMACEUTICALS INC 0.1%$248.5k20,400 -78% reduced
33 NUVATION BIO INC 0.0%$53.9k266,666 0% held
34 SURROZEN INC 0.0%$1.0k66,666 0% held

Weights are shares of the reported long US equity book (options excluded). Values are as filed, normalised to whole dollars. Share changes compare against the immediately preceding filing only.