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Which hedge funds own UPB? UPSTREAM BIO INC, Q2 2026 13F holders

36 tracked hedge funds disclosed a position in UPB (UPSTREAM BIO INC) in their Q2 2026 13F filings, worth $128.1m in total. The largest holder by portfolio weight is Decheng Capital LLC at 2.6% of its book. 9 opened a new position this quarter: Verdad Advisers, LP, Voleon Capital Management LP, Walleye Capital LLC, Prelude Capital Management, LLC. 7 exited: Prosight Management, LP, Nantahala Capital Management, LLC, ADAR1 Capital Management, LLC.

36
Holders
Tracked managers whose filing for the quarter reports a long equity position in the security.
9
New this quarter
Holders whose previous filing (at most two quarters earlier) did not report the security.
7
Exited this quarter
Tracked managers whose previous filing reported the security and whose filing for the quarter does not.
$6.5m
Inflow, new holders
Combined value of the positions the new holders reported for the quarter.
$9.9m
Outflow, exits
Combined value the exiting managers reported for the security in their previous filing.
$128m
Combined value
Sum of the holders' reported positions in the security.
2.9%
Share of managers holding
Holders as a share of tracked managers filing for that quarter. Comparable across the 2024 coverage expansion, where the raw holder count is not.

Holders, Q2 2026

36 rows
Decheng Capital LLC Hedge fund2.6%$18.9m2.72m0.0%held
Propel Bio Management, LLC Hedge fund1.3%$2.4m350,389+2.5%added
Orbimed Advisors LLC Hedge fund0.7%$39.4m5.69m0.0%held
Parkman Healthcare Partners LLC Hedge fund0.7%$6.5m935,247+19%added
Sphera Funds Management Ltd. Hedge fund0.2%$1.5m219,700−39%reduced
EntryPoint Capital, LLC Hedge fund0.2%$896k129,446+76%added
Stonepine Capital Management, LLC Hedge fund0.2%$231k33,432−4.5%reduced
Verdad Advisers, LP Hedge fund0.1%$151k21,810–new
Y-Intercept (Hong Kong) Ltd Hedge fund0.09%$4.8m693,555−31%reduced
Boxer Capital Management, LLC Hedge fund0.08%$1.0m150,0000.0%held
Diadema Partners LP Hedge fund0.05%$132k19,093−12%reduced
Voleon Capital Management LP Hedge fund0.04%$2.0m285,234–new
Gsa Capital Partners LLP Hedge fund0.03%$480k69,348+77%added
Trexquant Investment LP Hedge fund0.02%$3.2m466,430+164%added
Woodline Partners LP Hedge fund0.02%$5.8m831,4810.0%held
Walleye Capital LLC Hedge fund0.02%$3.4m498,490–new
Persistent Asset Partners Ltd Hedge fund0.01%$33.6k4,855−12%reduced
Schonfeld Strategic Advisors LLC Hedge fund0.01%$1.6m225,760+40%added
Quantbot Technologies LP Hedge fund0.01%$195k28,178+4150%added
Qube Research & Technologies Ltd Hedge fund0.01%$6.8m978,500+58%added
Prelude Capital Management, LLC Hedge fund0.01%$73.0k10,550–new
Millennium Management LLC Hedge fund0.01%$7.9m1.14m+22%added
Brevan Howard Capital Management LP Hedge fund0.0%$349k50,369–new
Entropy Technologies, LP Hedge fund0.0%$121k17,542−25%reduced
Point72 Asset Management, L.P. Hedge fund0.0%$3.1m453,011+154%added
D. E. Shaw & Co., Inc. Hedge fund0.0%$7.2m1.04m+26%added
Graham Capital Management, L.P. Hedge fund0.0%$156k22,508–new
Squarepoint Ops LLC Hedge fund0.0%$2.0m290,904+552%added
ExodusPoint Capital Management, LP Hedge fund0.0%$284k41,045−55%reduced
AQR Capital Management LLC Hedge fund0.0%$3.8m544,869+655%added
Renaissance Technologies LLC Hedge fund0.0%$909k131,300+111%added
Engineers Gate Manager LP Hedge fund0.0%$86.4k12,491–new
Arrowstreet Capital, Limited Partnership Hedge fund0.0%$2.5m357,756+93%added
Quarry LP Hedge fund0.0%$6.2k893–new
Two Sigma Investments, LP Hedge fund0.0%$293k42,325–new
Freestone Grove Partners LP Hedge fund0.0%$710.0%held