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Stonepine Capital Management, LLC: 13F holdings, Q2 2026

Hedge fund · SEC EDGAR filings (CIK 1440771) · Explore on the interactive board

Stonepine Capital Management, LLC disclosed 72 US equity positions worth $131.4m in its Q2 2026 13F filing (holdings as of June 30, 2026, filed August 17, 2026). Its largest position is VSTM at 9.7% of the reported book, followed by EOLS, TENX. The top ten holdings are 55.3% of the book, and the portfolio behaves like about 24 equal-weight positions. Versus the prior filing it opened 19 new positions, added to 23, reduced 25 and exited 9. Note: this manager's most recent filing is 3934 quarters behind the newest quarter on file, so these figures are history rather than current positioning.

This manager's most recent filing is 3934 quarter(s) behind the newest quarter on file. Treat these figures as history, not current positioning.
$131.4mreported US equity book
72positions
9.7%largest position
55.3%top 10 weight
23.99effective positions (1/HHI)
2quarters on file since Q1 2026

What does Stonepine Capital Management, LLC own? Top holdings as of June 30, 2026

Change is measured in shares against the previous filing (Q1 2026), so price moves do not read as decisions. This quarter: 19 new, 23 added, 25 reduced, 9 exited.

#StockSectorWeightValueSharesΔ sharesAction
1 VSTM VERASTEM INC Healthcare 9.7%$12.8m3,349,627 1% added
2 EOLS EVOLUS INC Healthcare 8.4%$11.0m1,590,162 -10% reduced
3 TENX TENAX THERAPEUTICS INC 7.3%$9.6m660,000 -32% reduced
4 NKTR NEKTAR THERAPEUTICS Healthcare 6.4%$8.4m120,654 42% added
5 ADMA ADMA BIOLOGICS INC Healthcare 4.7%$6.2m740,000 0% held
6 CAMP CAMP4 THERAPEUTICS CORP 4.6%$6.1m1,389,622 0% held
7 ELOXX PHARMACEUTICALS INC 4.2%$5.5m397,160 new
8 KZIA KAZIA THERAPEUTICS LTD 3.7%$4.9m345,179 0% held
9 INDV INDIVIOR PHARMACEUTICALS INC Healthcare 3.1%$4.1m100,000 new
10 CRBP CORBUS PHARMACEUTICALS HLDGS Healthcare 3.0%$4.0m425,000 11% added
11 MSLE SATELLOS BIOSCIENCE INC 2.8%$3.7m491,624 392% added
12 ZVRA ZEVRA THERAPEUTICS INC 2.8%$3.7m258,701 -46% reduced
13 ABEO ABEONA THERAPEUTICS INC Healthcare 2.6%$3.4m557,284 -25% reduced
14 EDSA EDESA BIOTECH INC 2.4%$3.2m456,439 1421% added
15 CABA CABALETTA BIO INC Healthcare 2.2%$2.9m917,100 1734% added
16 ANTX AN2 THERAPEUTICS INC 2.0%$2.7m551,692 -23% reduced
17 XLO XILIO THERAPEUTICS INC 1.6%$2.2m225,994 252% added
18 ACET ADICET BIO INC 1.6%$2.1m245,518 11% added
19 TELA TELA BIO INC 1.5%$2.0m2,662,427 2% added
20 AYTU AYTU BIOPHARMA INC 1.5%$2.0m912,921 15% added
21 CRIS CURIS INC 1.3%$1.7m3,312,185 -11% reduced
22 SPRB SPRUCE BIOSCIENCES INC 1.2%$1.6m28,795 new
23 OKYO OKYO PHARMA LTD 1.0%$1.3m862,996 2% added
24 KTTA PASITHEA THERAPEUTICS CORP 0.9%$1.1m2,201,468 165% added
25 SOL-GEL TECHNOLOGIES LTD 0.8%$1.1m14,469 -48% reduced
26 LUNG PULMONX CORP Healthcare 0.8%$1.1m815,436 6% added
27 XFOR X4 PHARMACEUTICALS INC 0.8%$1.1m224,989 -33% reduced
28 INAB IN8BIO INC 0.7%$980.4k695,287 5% added
29 MLTX MOONLAKE IMMUNOTHERAPEUTICS Healthcare 0.7%$973.5k50,000 new
30 QUOIN PHARMACEUTICALS LTD 0.7%$965.5k199,486 273% added
31 MXCT MAXCYTE INC Healthcare 0.7%$924.5k751,606 -25% reduced
32 PHAT PHATHOM PHARMACEUTICALS INC Healthcare 0.7%$922.4k85,010 70% added
33 AZITRA INC 0.7%$886.9k5,285,476 new
34 CNTB CONNECT BIOPHARMA HLDGS LTD 0.7%$866.9k364,254 18% added
35 HELP CYBIN INC 0.7%$854.5k129,280 -4% reduced
36 RARE ULTRAGENYX PHARMACEUTICAL IN Healthcare 0.6%$834.8k25,000 new
37 IKT INHIBIKASE THERAPEUTICS INC 0.6%$804.2k396,179 -59% reduced
38 ZNTL ZENTALIS PHARMACEUTICALS INC Healthcare 0.6%$783.7k161,583 -40% reduced
39 CTMX CYTOMX THERAPEUTICS INC. Healthcare 0.6%$768.8k205,000 2% added
40 NVCT NUVECTIS PHARMA INC 0.6%$735.6k40,000 new
41 CBIO CRESCENT BIOPHARMA INC. 0.5%$720.0k40,000 -53% reduced
42 PMVP PMV PHARMACEUTICALS INC Healthcare 0.5%$718.4k536,086 -24% reduced
43 ORKA ORUKA THERAPEUTICS INC Healthcare 0.5%$713.8k7,500 new
44 RADIOPHARM THERANOSTICS LTD 0.5%$670.5k51,000,000 0% held
45 OKUR ONKURE THERAPEUTICS INC 0.5%$595.9k130,684 -1% reduced
46 NERVGEN PHARMA CORP 0.4%$559.7k271,678 new
47 CALC CALCIMEDICA INC 0.4%$544.9k622,432 new
48 ARVN ARVINAS INC Healthcare 0.4%$498.6k60,000 118% added
49 BIOA BIOAGE LABS INC 0.4%$490.2k20,000 -60% reduced
50 IRD OPUS GENETICS INC 0.3%$414.0k100,718 47% added

What did Stonepine Capital Management, LLC sell? Positions exited since the previous filing

StockPrior weightPrior value
XOMA ROYALTY CORPORATION42.2%$2.2m
SRZN SURROZEN INC18.6%$961.4k
VRCA VERRICA PHARMACEUTICALS INC10.2%$527.6k
CADL CANDEL THERAPEUTICS INC9.7%$502.2k
ESTA ESTABLISHMENT LABS HLDGS INC6.6%$340.7k
JANX JANUX THERAPEUTICS INC5.4%$278.0k
OABI OMNIAB INC5.0%$257.6k
ELDN ELEDON PHARMACEUTICALS INC2.1%$107.8k
BCAB BIOATLA INC0.2%$10.5k

Sector mix

SectorWeight
Healthcare47.1%

Sectors cover positions whose ticker resolved to a sector; the remainder is unclassified, not cash.

Filing history

QuarterPositionsEquity value
Q2 202672$131.4m
Q1 202666$113.7m

How concentrated is Stonepine Capital Management, LLC's portfolio?

Across every quarter Stonepine Capital Management, LLC has filed, its median largest position is 12.6% of the book and its median top-ten weight is 59.8%, which WhaleCreep classifies as concentrated (the gate is a median largest position of 5%). Of 13.0 completed holding spells, the median lasted 1.0 quarters; 72.0 positions are still open and their final length is unknown.