Darwin Global Management, Ltd. 13F holdings, Q4 2025
Holdings as of December 31, 2025 · filings on SEC EDGAR · latest filing →
Darwin Global Management, Ltd. disclosed 6 US equity positions worth $4.9bn in its Q4 2025 13F filing. The largest position was INSM at 73.8% of the reported book, followed by BLTE and ABVX. Against the Q3 2025 filing, it opened 3 new positions, added to 1 and reduced 0 among the top 6 holdings.
What did Darwin Global Management, Ltd. own in Q4 2025? Top 6 positions
| # | Stock | Sector | Weight | Value | Shares | Δ shares | vs Q3 2025 |
|---|---|---|---|---|---|---|---|
| 1 | INSM INSMED INC | Healthcare | 73.8% | $3.6bn | 20,933,277 | 2% | added |
| 2 | BLTE BELITE BIO INC | Healthcare | 9.9% | $486.9m | 3,027,704 | – | new |
| 3 | ABVX ABIVAX SA | 8.9% | $439.7m | 3,178,501 | 0% | held | |
| 4 | CDTX CIDARA THERAPEUTICS INC | 4.5% | $220.2m | 997,196 | 0% | held | |
| 5 | WVE WAVE LIFE SCIENCES LTD | Healthcare | 2.5% | $125.2m | 7,298,421 | – | new |
| 6 | CAPR CAPRICOR THERAPEUTICS INC | Healthcare | 0.5% | $23.2m | 800,000 | – | new |
Weights are shares of the reported long US equity book (options excluded). Values are as filed, normalised to whole dollars. Share changes compare against the immediately preceding filing only.