WhaleCreep
HomeFunds › Sio Capital Management, LLC

Sio Capital Management, LLC: 13F holdings, Q2 2026

Hedge fund · SEC EDGAR filings (CIK 1482416) · Explore on the interactive board

Sio Capital Management, LLC disclosed 57 US equity positions worth $583.5m in its Q2 2026 13F filing (holdings as of June 30, 2026, filed August 14, 2026). Its largest position is AVR at 9.4% of the reported book, followed by COR, MMS. The top ten holdings are 50.1% of the book, and the portfolio behaves like about 26 equal-weight positions. Versus the prior filing it opened 15 new positions, added to 10, reduced 21 and exited 25. Note: this manager's most recent filing is 3934 quarters behind the newest quarter on file, so these figures are history rather than current positioning.

This manager's most recent filing is 3934 quarter(s) behind the newest quarter on file. Treat these figures as history, not current positioning.
$583.5mreported US equity book
57positions
9.4%largest position
50.1%top 10 weight
25.9effective positions (1/HHI)
2quarters on file since Q1 2026

What does Sio Capital Management, LLC own? Top holdings as of June 30, 2026

Change is measured in shares against the previous filing (Q1 2026), so price moves do not read as decisions. This quarter: 15 new, 10 added, 21 reduced, 25 exited.

#StockSectorWeightValueSharesΔ sharesAction
1 AVR ANTERIS TECHNOLOGIES GLOBAL 9.4%$54.6m5,545,984 3% added
2 COR CENCORA INC Healthcare 8.4%$49.1m173,588 72% added
3 MMS MAXIMUS INC Industrials 6.6%$38.5m715,267 -7% reduced
4 ALLO ALLOGENE THERAPEUTICS INC Healthcare 4.7%$27.7m13,323,431 new
5 GMED GLOBUS MED INC Healthcare 4.1%$23.8m301,816 new
6 GSK GSK PLC Healthcare 3.9%$22.9m436,700 13% added
7 TYRA TYRA BIOSCIENCES INC Healthcare 3.8%$22.2m695,315 15% added
8 WAY WAYSTAR HLDG CORP Healthcare 3.3%$19.0m925,834 -44% reduced
9 IDYA IDEAYA BIOSCIENCES INC Healthcare 3.1%$17.9m480,383 new
10 ORKA ORUKA THERAPEUTICS INC Healthcare 2.9%$16.9m177,118 34% added
11 CI THE CIGNA GROUP Healthcare 2.7%$15.9m57,750 new
12 SNY SANOFI SA Healthcare 2.7%$15.5m364,200 52% added
13 ICLR ICON PUB LTD CO Healthcare 2.6%$15.3m88,186 -71% reduced
14 VTRS VIATRIS INC Healthcare 2.6%$15.2m954,299 new
15 CROSS CTRY HEALTHCARE INC 2.5%$14.5m1,098,393 0% held
16 RAPP RAPPORT THERAPEUTICS INC 2.2%$12.8m307,657 -16% reduced
17 ABT ABBOTT LABORATORIES Healthcare 2.0%$11.7m128,656 -31% reduced
18 CELC CELCUITY INC Healthcare 2.0%$11.5m110,022 -43% reduced
19 ZBH ZIMMER BIOMET HOLDINGS INC Healthcare 1.9%$11.3m131,445 110% added
20 REGN REGENERON PHARMACEUTICALS Healthcare 1.9%$11.2m18,000 new
21 BMY BRISTOL-MYERS SQUIBB CO Healthcare 1.9%$11.1m193,500 new
22 MDT MEDTRONIC PLC Healthcare 1.9%$11.1m142,500 new
23 VIR VIR BIOTECHNOLOGY INC Healthcare 1.9%$11.0m1,075,274 -28% reduced
24 SENS SENSEONICS HLDGS INC 1.6%$9.0m1,592,692 1276% added
25 EYPT EYEPOINT INC Healthcare 1.5%$8.9m623,130 -14% reduced
26 HELP CYBIN INC 1.5%$8.6m1,300,000 new
27 ANIP ANI PHARMACEUTICALS INC Healthcare 1.4%$8.1m97,305 -63% reduced
28 TARA PROTARA THERAPEUTICS INC 1.3%$7.3m1,921,872 -2% reduced
29 RLMD RELMADA THERAPEUTICS INC Healthcare 1.2%$6.9m1,003,562 4% added
30 TNGX TANGO THERAPEUTICS INC Healthcare 1.1%$6.5m208,500 new
31 AQST AQUESTIVE THERAPEUTICS INC 1.1%$6.2m1,486,175 -23% reduced
32 DNTH DIANTHUS THERAPEUTICS INC Healthcare 1.0%$5.8m59,254 -84% reduced
33 SION SIONNA THERAPEUTICS INC Healthcare 1.0%$5.6m127,808 -57% reduced
34 OCUL OCULAR THERAPEUTIX INC Healthcare 0.9%$5.3m539,493 -44% reduced
35 ZBIO ZENAS BIOPHARMA INC 0.9%$5.3m208,557 -37% reduced
36 DRUG BRIGHT MINDS BIOSCIENCES INC Healthcare 0.9%$5.2m73,952 -14% reduced
37 OKUR ONKURE THERAPEUTICS INC 0.8%$4.9m1,078,965 0% held
38 SVRA SAVARA INC Healthcare 0.7%$3.8m617,675 1% added
39 PMVP PMV PHARMACEUTICALS INC Healthcare 0.6%$3.5m2,634,137 -14% reduced
40 AVAH AVEANNA HEALTHCARE HLDGS INC Healthcare 0.5%$3.2m369,036 new
41 OVID OVID THERAPEUTICS INC Healthcare 0.5%$2.7m1,005,334 -20% reduced
42 IMNM IMMUNOME INC Healthcare 0.5%$2.6m124,168 -25% reduced
43 ANTX AN2 THERAPEUTICS INC 0.4%$2.6m529,933 -19% reduced
44 SERINA THERAPEUTICS INC 0.3%$1.9m1,000,000 0% held
45 ALGS ALIGOS THERAPEUTICS INC 0.3%$1.9m327,237 0% held
46 IBIO IBIO INC 0.3%$1.6m904,268 0% held
47 XLO XILIO THERAPEUTICS INC 0.3%$1.5m152,464 0% held
48 AORT ARTIVION INC Healthcare 0.2%$1.1m48,481 new
49 BBOT BRIDGEBIO ONCOLOGY THERAPEUT 0.2%$995.4k130,628 0% held
50 TELA TELA BIO INC 0.1%$477.2k636,300 0% held

What did Sio Capital Management, LLC sell? Positions exited since the previous filing

StockPrior weightPrior value
CORT CORCEPT THERAPEUTICS INC12.7%$27.2m
LIVN LIVANOVA PLC12.5%$26.8m
EMBC EMBECTA CORP7.6%$16.3m
ABVX ABIVAX SA7.0%$15.1m
HAE HAEMONETICS CORP MASS5.8%$12.4m
TFX TELEFLEX INCORPORATED5.3%$11.3m
BMRN BIOMARIN PHARMACEUTICAL INC5.1%$11.0m
GPCR STRUCTURE THERAPEUTICS INC4.7%$10.1m
BHVN BIOHAVEN LTD4.6%$9.8m
MNPR MONOPAR THERAPEUTICS INC4.4%$9.5m
CRNXGBP CRINETICS PHARMACEUTICALS IN4.2%$9.1m
EWTX EDGEWISE THERAPEUTICS INC3.9%$8.5m
CMPS COMPASS PATHWAYS PLC3.9%$8.3m
QDEL QUIDELORTHO CORP2.7%$5.9m
REPL REPLIMUNE GROUP INC2.6%$5.5m
OGN ORGANON & CO2.4%$5.2m
IRON DISC MEDICINE INC1.9%$4.2m
IART INTEGRA LIFESCIENCES HLDGS C1.7%$3.6m
PROQR THERAPEUTICS N V1.5%$3.2m
SI SHOULDER INNOVATIONS INC1.4%$3.1m
KYMR KYMERA THERAPEUTICS INC1.3%$2.7m
CNTX CONTEXT THERAPEUTICS INC1.1%$2.4m
HYPR HYPERFINE INC0.5%$1.1m
FHTX FOGHORN THERAPEUTICS INC0.3%$587.4k
430 TERNS PHARMACEUTICALS INC0.2%$532.5k

Sector mix

SectorWeight
Healthcare70.2%
Industrials6.6%

Sectors cover positions whose ticker resolved to a sector; the remainder is unclassified, not cash.

Filing history

QuarterPositionsEquity value
Q2 202657$583.5m
Q1 202673$693.9m

How concentrated is Sio Capital Management, LLC's portfolio?

Across every quarter Sio Capital Management, LLC has filed, its median largest position is 8.2% of the book and its median top-ten weight is 47.8%, which WhaleCreep classifies as concentrated (the gate is a median largest position of 5%). Of 31.0 completed holding spells, the median lasted 1.0 quarters; 57.0 positions are still open and their final length is unknown.