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MPM Asset Management LLC: 13F holdings, Q3 2025

Hedge fund · SEC EDGAR filings (CIK 1263048) · Explore on the interactive board

MPM Asset Management LLC disclosed 4 US equity positions worth $44.5m in its Q3 2025 13F filing (holdings as of September 30, 2025, filed November 14, 2025). Its largest position is TRDA at 57.1% of the reported book, followed by DYN, HOWL. The top ten holdings are 100.0% of the book, and the portfolio behaves like about 2 equal-weight positions. Versus the prior filing it opened 0 new positions, added to 0, reduced 0 and exited 1. Note: this manager's most recent filing is 3 quarters behind the newest quarter on file, so these figures are history rather than current positioning.

This manager's most recent filing is 3 quarter(s) behind the newest quarter on file. Treat these figures as history, not current positioning.
$44.5mreported US equity book
4positions
57.1%largest position
100.0%top 10 weight
2.49effective positions (1/HHI)
5quarters on file since Q3 2024

What does MPM Asset Management LLC own? Top holdings as of September 30, 2025

Change is measured in shares against the previous filing (Q2 2025), so price moves do not read as decisions. This quarter: 0 new, 0 added, 0 reduced, 1 exited.

#StockSectorWeightValueSharesΔ sharesAction
1 TRDA Entrada Therapeutics, Inc. 57.1%$25.4m4,381,062 0% held
2 DYN Dyne Therapeutics, Inc. Healthcare 19.4%$8.6m682,376 0% held
3 HOWL Werewolf Therapeutics, Inc. 19.1%$8.5m4,309,860 0% held
4 RPTX Repare Therapeutics, Inc. 4.4%$2.0m1,121,318 0% held

What did MPM Asset Management LLC sell? Positions exited since the previous filing

StockPrior weightPrior value
ADAPY Adaptimmune Therapeutics plc100.0%$1.2m

Sector mix

SectorWeight
Healthcare19.4%

Sectors cover positions whose ticker resolved to a sector; the remainder is unclassified, not cash.

Filing history

QuarterPositionsEquity value
Q3 20254$44.5m
Q2 20255$43.3m
Q1 20256$69.4m
Q4 20246$124.4m
Q3 20246$145.3m

How concentrated is MPM Asset Management LLC's portfolio?

Across every quarter MPM Asset Management LLC has filed, its median largest position is 57.1% of the book and its median top-ten weight is 100.0%, which WhaleCreep classifies as concentrated (the gate is a median largest position of 5%). Of 2.0 completed holding spells, the median lasted 3.5 quarters; 4.0 positions are still open and their final length is unknown.