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EcoR1 Capital, LLC 13F holdings, Q2 2026

Holdings as of June 30, 2026 · filings on SEC EDGAR · this is the latest filing on record

EcoR1 Capital, LLC disclosed 31 US equity positions worth $2.0bn in its Q2 2026 13F filing. The largest position was ZYME at 29.8% of the reported book, followed by ANAB and AKTS. Against the Q1 2026 filing, it opened 9 new positions, added to 3 and reduced 4 among the top 31 holdings.

← Q1 2026

What did EcoR1 Capital, LLC own in Q2 2026? Top 31 positions

#StockSectorWeightValueSharesΔ sharesvs Q1 2026
1 ZYME ZYMEWORKS INC Healthcare 29.8%$600.4m22,970,388 0% held
2 ANAB ANAPTYSBIO INC Healthcare 26.4%$531.9m7,880,094 0% held
3 AKTS AKTIS ONCOLOGY INC 7.7%$155.5m4,824,469 0% held
4 CGON CG ONCOLOGY INC Healthcare 5.3%$106.2m1,494,300 36% added
5 ETON ETON PHARMACEUTICALS INC 3.9%$78.6m2,171,938 0% held
6 CRSP CRISPR THERAPEUTICS AG Healthcare 3.8%$75.8m1,389,276 0% held
7 ORIC ORIC PHARMACEUTICALS INC Healthcare 3.6%$72.9m6,728,116 0% held
8 TRAX FIRST TRACKS BIOTHERAPEUTICS 3.2%$63.9m3,174,519 new
9 LKFT LAKEFRONT BIOTHERAPEUTICS NV Healthcare 2.5%$50.0m1,667,119 0% held
10 NGNE NEUROGENE INC 2.0%$40.0m1,271,342 0% held
11 STOK STOKE THERAPEUTICS INC Healthcare 1.2%$24.0m735,000 635% added
12 FULC FULCRUM THERAPEUTICS INC Healthcare 1.2%$24.0m6,549,866 new
13 LEGN LEGEND BIOTECH CORP Healthcare 1.1%$23.1m800,000 new
14 BBOT BRIDGEBIO ONCOLOGY THERAPEUT 1.1%$21.5m2,823,126 0% held
15 MBX MBX BIOSCIENCES INC Healthcare 1.1%$21.4m388,500 -50% reduced
16 ZBIO ZENAS BIOPHARMA INC 1.0%$20.0m789,500 0% held
17 ATRA ATARA BIOTHERAPEUTICS INC 0.9%$17.8m1,552,000 1458% added
18 RLAY RELAY THERAPEUTICS INC Healthcare 0.6%$13.1m697,948 -63% reduced
19 AURA AURA BIOSCIENCES INC 0.6%$11.8m1,666,667 new
20 ODYSSEY THERAPEUTICS INC 0.5%$10.4m555,555 new
21 EIKN EIKON THERAPEUTICS INC 0.5%$9.6m732,606 0% held
22 PHVS PHARVARIS N V Healthcare 0.4%$8.1m235,000 new
23 ZURA ZURA BIO LTD Healthcare 0.3%$7.0m1,179,715 0% held
24 PHAT PHATHOM PHARMACEUTICALS INC Healthcare 0.3%$6.8m625,000 0% held
25 NRIX NURIX THERAPEUTICS INC Healthcare 0.3%$6.6m270,000 new
26 ERAS ERASCA INC Healthcare 0.3%$6.0m330,000 -63% reduced
27 ELOXX PHARMACEUTICALS INC 0.3%$5.6m400,000 new
28 AARD AARDVARK THERAPEUTICS INC 0.1%$2.3m396,194 new
29 HELIX ACQUISITION CORP III USD 0.1%$2.1m200,000 0% held
30 MREO MEREO BIOPHARMA GROUP PLC Healthcare 0.0%$317.7k1,000,000 -93% reduced
31 SURROZEN INC 0.0%$115.3k4,444 0% held

Weights are shares of the reported long US equity book (options excluded). Values are as filed, normalised to whole dollars. Share changes compare against the immediately preceding filing only.