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Deerfield Management Company, L.P.: 13F holdings, Q2 2026

Hedge fund · SEC EDGAR filings (CIK 1009258) · Explore on the interactive board

Deerfield Management Company, L.P. disclosed 82 US equity positions worth $9.6bn in its Q2 2026 13F filing (holdings as of June 30, 2026, filed August 14, 2026). Its largest position is NUVALENT INC at 22.2% of the reported book, followed by BROOKDALE SR LIVING INC, RVMD. The top ten holdings are 53.2% of the book, and the portfolio behaves like about 15 equal-weight positions. Versus the prior filing it opened 13 new positions, added to 13, reduced 12 and exited 13. Note: this manager's most recent filing is 3934 quarters behind the newest quarter on file, so these figures are history rather than current positioning.

This manager's most recent filing is 3934 quarter(s) behind the newest quarter on file. Treat these figures as history, not current positioning.
$9.6bnreported US equity book
82positions
22.2%largest position
53.2%top 10 weight
15.04effective positions (1/HHI)
2quarters on file since Q1 2026

What does Deerfield Management Company, L.P. own? Top holdings as of June 30, 2026

Change is measured in shares against the previous filing (Q1 2026), so price moves do not read as decisions. This quarter: 13 new, 13 added, 12 reduced, 13 exited.

#StockSectorWeightValueSharesΔ sharesAction
1 NUVALENT INC 22.2%$2.1bn17,248,450 0% held
2 BROOKDALE SR LIVING INC 6.1%$585.7m306,885,000 0% held
3 RVMD REVOLUTION MEDICINES INC Healthcare 4.7%$448.0m2,392,000 4% added
4 PRAX PRAXIS PRECISION MEDICINES I Healthcare 3.4%$322.5m963,351 0% held
5 VTRS VIATRIS INC Healthcare 3.3%$320.9m20,206,170 0% held
6 CNC CENTENE CORP DEL Healthcare 3.3%$314.6m4,901,000 -17% reduced
7 REVOLUTION MEDICINES INC 2.6%$251.7m200,000,000 new
8 UTHR UNITED THERAPEUTICS CORP DEL Healthcare 2.6%$247.6m457,000 0% held
9 ARROWHEAD PHARMACEUTICALS IN 2.5%$240.5m200,000,000 0% held
10 LEGN LEGEND BIOTECH CORP Healthcare 2.5%$235.0m8,137,638 6% added
11 COGT COGENT BIOSCIENCES INC Healthcare 2.0%$193.7m5,006,104 -45% reduced
12 GMAB GENMAB A/S Healthcare 2.0%$188.6m6,865,000 179% added
13 BKD BROOKDALE SR LIVING INC Healthcare 2.0%$187.2m11,637,032 0% held
14 VERA VERA THERAPEUTICS INC Healthcare 1.8%$168.1m3,916,400 5% added
15 IONS IONIS PHARMACEUTICALS INC Healthcare 1.6%$157.0m1,979,669 0% held
16 CELC CELCUITY INC Healthcare 1.6%$151.8m1,451,014 -15% reduced
17 BCRX BIOCRYST PHARMACEUTICALS INC Healthcare 1.6%$151.0m15,096,403 0% held
18 NEWAMSTERDAM PHARMA COMPANY 1.5%$144.5m4,264,789 0% held
19 ACHC ACADIA HEALTHCARE COMPANY IN Healthcare 1.4%$133.5m4,520,000 0% held
20 TNGX TANGO THERAPEUTICS INC Healthcare 1.4%$131.0m4,190,611 1% added
21 AHCO ADAPTHEALTH CORP Healthcare 1.2%$119.6m11,477,730 0% held
22 PHVS PHARVARIS N V Healthcare 1.2%$116.7m3,376,042 8% added
23 CELCUITY INC 1.2%$113.8m100,000,000 new
24 ARWR ARROWHEAD PHARMACEUTICALS IN Healthcare 1.2%$113.2m1,389,055 -12% reduced
25 DNTH DIANTHUS THERAPEUTICS INC Healthcare 1.1%$109.7m1,125,313 10% added
26 LRMR LARIMAR THERAPEUTICS INC Healthcare 1.1%$108.6m35,606,974 0% held
27 MLYS MINERALYS THERAPEUTICS INC Healthcare 1.1%$106.8m3,958,000 new
28 ALIGNMENT HEALTHCARE INC 1.1%$103.8m61,000,000 0% held
29 IDYA IDEAYA BIOSCIENCES INC Healthcare 1.1%$101.2m2,714,503 77% added
30 XENE XENON PHARMACEUTICALS INC Healthcare 1.0%$97.5m1,615,696 0% held
31 IONIS PHARMACEUTICALS INC 1.0%$93.1m60,000,000 0% held
32 SVRA SAVARA INC Healthcare 0.9%$83.6m13,569,000 0% held
33 LNTH LANTHEUS HLDGS INC Healthcare 0.9%$83.5m752,999 -9% reduced
34 SNDX SYNDAX PHARMACEUTICALS INC Healthcare 0.9%$82.6m3,779,900 0% held
35 ZENAS BIOPHARMA INC 0.8%$80.3m67,200,000 3% added
36 BMRN BIOMARIN PHARMACEUTICAL INC Healthcare 0.8%$76.3m1,332,836 57% added
37 PFE PFIZER INC Healthcare 0.8%$73.2m3,040,000 0% held
38 INDV INDIVIOR PHARMACEUTICALS INC Healthcare 0.7%$67.7m1,648,895 -47% reduced
39 BIO BIO RAD LABS INC Healthcare 0.7%$66.4m226,070 0% held
40 SPRY ARS PHARMACEUTICALS INC Healthcare 0.6%$60.1m7,503,812 0% held
41 STOK STOKE THERAPEUTICS INC Healthcare 0.6%$59.7m1,823,500 0% held
42 GPCR STRUCTURE THERAPEUTICS INC Healthcare 0.6%$58.3m1,086,000 41% added
43 NVST ENVISTA HOLDINGS CORPORATION Healthcare 0.6%$58.2m2,210,100 0% held
44 INSP INSPIRE MED SYS INC Healthcare 0.6%$57.9m1,296,862 -52% reduced
45 CDNA CAREDX INC Healthcare 0.6%$56.9m1,997,618 -9% reduced
46 BSX BOSTON SCIENTIFIC CORP Healthcare 0.6%$56.1m1,315,000 new
47 BLTE BELITE BIO INC Healthcare 0.6%$55.0m357,199 17% added
48 PARABILIS MEDICINES INC 0.5%$51.5m1,880,704 new
49 CERT CERTARA INC Healthcare 0.5%$49.2m7,512,928 -4% reduced
50 IRON DISC MEDICINE INC Healthcare 0.5%$48.1m657,000 0% held

What did Deerfield Management Company, L.P. sell? Positions exited since the previous filing

StockPrior weightPrior value
MIRM MIRUM PHARMACEUTICALS INC33.9%$209.4m
CATALYST PHARMACEUTICALS INC15.8%$97.6m
NBIX NEUROCRINE BIOSCIENCES INC13.0%$80.4m
DAWNGBX DAY ONE BIOPHARMACEUTICALS I12.9%$79.8m
ENHABIT INC10.8%$66.9m
KYMR KYMERA THERAPEUTICS INC7.6%$46.7m
CMPX COMPASS THERAPEUTICS INC3.1%$19.1m
TSHA TAYSHA GENE THERAPIES INC2.0%$12.2m
CGEM CULLINAN THERAPEUTICS INC0.9%$5.5m
BIOMX INC0.1%$492.8k
MANE VERADERMICS INC0.1%$315.8k
QUANTUM SI INC0.0%$36.2k
MYGN MYRIAD GENETICS INC0.0%$2.3k

Sector mix

SectorWeight
Healthcare57.3%

Sectors cover positions whose ticker resolved to a sector; the remainder is unclassified, not cash.

Filing history

QuarterPositionsEquity value
Q2 202682$9.6bn
Q1 202682$8.5bn

How concentrated is Deerfield Management Company, L.P.'s portfolio?

Across every quarter Deerfield Management Company, L.P. has filed, its median largest position is 21.5% of the book and its median top-ten weight is 52.0%, which WhaleCreep classifies as concentrated (the gate is a median largest position of 5%). Of 12.0 completed holding spells, the median lasted 1.0 quarters; 82.0 positions are still open and their final length is unknown.