Crestline Management, L.P. 13F holdings, Q4 2025
Holdings as of December 31, 2025 · filings on SEC EDGAR · latest filing →
Crestline Management, L.P. disclosed 3 US equity positions worth $53.3m in its Q4 2025 13F filing. The largest position was DNLI at 87.0% of the reported book, followed by SANA and EGHT. Against the Q3 2025 filing, it opened 0 new positions, added to 0 and reduced 2 among the top 3 holdings.
What did Crestline Management, L.P. own in Q4 2025? Top 3 positions
| # | Stock | Sector | Weight | Value | Shares | Δ shares | vs Q3 2025 |
|---|---|---|---|---|---|---|---|
| 1 | DNLI DENALI THERAPEUTICS INC | Healthcare | 87.0% | $46.4m | 2,810,732 | -18% | reduced |
| 2 | SANA SANA BIOTECHNOLOGY INC | Healthcare | 9.3% | $5.0m | 1,220,937 | -33% | reduced |
| 3 | EGHT 8X8 INC NEW | Technology | 3.7% | $2.0m | 990,580 | 0% | held |
Weights are shares of the reported long US equity book (options excluded). Values are as filed, normalised to whole dollars. Share changes compare against the immediately preceding filing only.